Anti-LAIR1 antibody [113] - Low endotoxin, Azide free
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(1 Publication)
Armenian hamster Monoclonal LAIR1 antibody. Carrier free. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 1 publication. Immunogen corresponding to Cell preparation containing Lair1 protein.
View Alternative Names
CD305, Leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, mLAIR1, Lair1
- Flow Cyt
Supplier Data
Flow Cytometry - Anti-LAIR1 antibody [113] - Low endotoxin, Azide free (AB171239)
Flow cytometry analysis of C57B1/6 splenocytes (total viable F4/80 positive cells) labelling LAIR1 with ab171239 at 0.125μg (blue line) and with Purified Armenian Hamster IgG control (purple line), followed by anti-Armenian Hamster IgG PE.
Related conjugates and formulations (1)
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578 PE
PE Anti-LAIR1 antibody [113]
Reactivity data
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Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
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Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
LAIR1 functions by modulating immune responses and maintaining homeostasis in the immune system. It is a part of a complex pathway involved in inhibitory signaling. When LAIR1 binds to its ligand such as collagen it transduces a signal that reduces activation of immune cells. This inhibition ensures that immune cells do not become overactive which could otherwise lead to tissue damage.
Pathways
LAIR1 participates in immune checkpoint regulation and collagen interaction pathways. It interacts with proteins such as ITIM-containing molecules which transmit inhibitory signals essential for regulating immune cell activation. It also indirectly connects to the TGF-beta signaling pathway which is vital for controlling cell differentiation and immune regulation.
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Publications (1)
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Nature cell biology 17:665-77 PubMed25915125
2015
Applications
WB
Species
Unspecified reactive species
Product promise
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