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AB233510

Anti-LCN8 antibody

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(1 Publication)

Rabbit Polyclonal LCN8 antibody. Suitable for WB, IHC-P and reacts with Mouse samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Mouse Lcn8 aa 1 to C-terminus.

View Alternative Names

Epididymal-specific lipocalin-8, Epididymal 17 kDa lipocalin, EP17, mEP17, Lcn8

6 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LCN8 antibody (AB233510)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LCN8 antibody (AB233510)

Paraffin-embedded mouse kidney tissue stained for LCN8 using ab233510 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LCN8 antibody (AB233510)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LCN8 antibody (AB233510)

Paraffin-embedded mouse ovary tissue stained for LCN8 using ab233510 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LCN8 antibody (AB233510)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LCN8 antibody (AB233510)

Paraffin-embedded mouse vas deferens tissue stained for LCN8 using ab233510 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LCN8 antibody (AB233510)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LCN8 antibody (AB233510)

Paraffin-embedded mouse uterus tissue stained for LCN8 using ab233510 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Western blot - Anti-LCN8 antibody (AB233510)
  • WB

Supplier Data

Western blot - Anti-LCN8 antibody (AB233510)

All lanes:

Western blot - Anti-LCN8 antibody (ab233510) at 3 µg/mL

All lanes:

Mouse testis lysate

Secondary

All lanes:

HRP-Linked Guinea pig Anti-Rabbit at 1/2000 dilution

Predicted band size: 19 kDa

false

Western blot - Anti-LCN8 antibody (AB233510)
  • WB

Supplier Data

Western blot - Anti-LCN8 antibody (AB233510)

All lanes:

Western blot - Anti-LCN8 antibody (ab233510) at 3 µg/mL

All lanes:

Recombinant mouse LCN8 protein

Secondary

All lanes:

HRP-Linked Guinea pig Anti-Rabbit at 1/2000 dilution

Predicted band size: 19 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Mouse Lcn8 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q924P3

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-2 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
ab233510 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Storage buffer
pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

LCN8 also known as Lipocalin-8 is part of the lipocalin family. It plays role mechanically in small molecule transport and storage. This protein has a molecular mass around 20 kDa. Researchers observe its expression in various tissues with significant presence in the kidney and liver. LCN8 is also known to bind and transport various small hydrophobic molecules.
Biological function summary

This protein contributes to molecule transport and cellular homeostasis. LCN8 is known to form part of a larger complex with other lipocalin family members which lets it efficiently bind and release ligands based on the cell's needs. Its activity impacts cellular metabolism by influencing the distribution of essential biomarkers and metabolites.

Pathways

LCN8 plays a significant role in lipid metabolism and signal transduction. In the lipid metabolism pathway it cooperates with proteins like LCN2 to modulate the transport of fatty acids. Similarly in signal transduction its activity can affect pathways involving lipophilic hormone signaling providing important links and modulations for cellular communication.

LCN8 has associations with metabolic disorders including obesity and diabetes. Researchers have observed altered levels of LCN8 in patients with obesity suggesting it might influence fat storage and insulin sensitivity. In diabetes its relationship with inflammation and metabolic regulation has implications for disease progression. LCN2 is another protein implicated in these disorders sharing some overlapping functions and pathways with LCN8.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May play a role in male fertility. May act as a retinoid carrier protein within the epididymis.
See full target information Lcn8
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

BMC cancer 25:1417 PubMed40898094

2025

KRAS mutation promotes immune escape of lung adenocarcinoma via ZNF24/SLC7A5/PD-L1 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Leilei Li,Qiang Feng,Ya Jiang,Lilin Yang,Hong Fang,Wenmang Xu,Yuanyuan Wang,Xinyan Pan,Julun Yang
View all publications
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Product promise

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