Rabbit Polyclonal LENG8 antibody. Suitable for WB, IHC-P and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human LENG8 aa 450-700.
Images
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
Preservative: 0.02% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Human LENG8 aa 450-700. The exact immunogen used to generate this antibody is proprietary information. Database link Q96PV6
Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Human | Tested | Tested |
| Mouse | Predicted | Predicted |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/1000.00000 - 1/2000.00000 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info - | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 5 µg/mL | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info - | Notes - |
Target data
Alternative names
KIAA1932, LENG8, Leukocyte receptor cluster member 8
Recommended products
Rabbit Polyclonal LENG8 antibody. Suitable for WB, IHC-P and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human LENG8 aa 450-700.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
Preservative: 0.02% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human LENG8 aa 450-700. The exact immunogen used to generate this antibody is proprietary information. Database link Q96PV6
- Purification technique
- Affinity purification
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
LENG8 also known as Leukocyte Receptor Cluster Member 8 is a protein that plays an important role in immune signaling. The molecular weight of LENG8 is approximately 25 kDa. LENG8 shows expression mainly in immune-related tissues like the spleen and lymph nodes indicating its role in the immune system. Its expression patterns suggest a functional role in immune cell interaction and signaling.
- Biological function summary
The actions of LENG8 are tied to immune cell interaction within the leukocyte receptor cluster. It does not work as an isolated protein but participates as part of a broader protein network. This cluster involves several receptors linked to immune modulation. LENG8 possibly influences the regulation of immune responses contributing to maintaining immune homeostasis.
- Pathways
Researchers have connected LENG8 to immune-related signaling pathways such as the cytokine receptor signaling pathway. Its involvement here suggests interactions with various cytokine receptors and other leukocyte receptors. These interactions place LENG8 in the broader context of immune cell activation and communication potentially interacting with proteins such as IL-2 and IL-4 which are key players in controlling immune responses.
- Associated diseases and disorders
LENG8's role in immune regulation implies a potential connection to autoimmune diseases like rheumatoid arthritis. Dysfunction or altered expression of LENG8 might influence disease progression due to its impact on immune cell signaling. In rheumatoid arthritis proteins such as TNF-alpha and IL-6 which regulate inflammatory responses might exhibit altered interactions with the pathways that involve LENG8 contributing to the disease pathology.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
3 product images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LENG8 antibody (ab230864)
Formalin-fixed, paraffin-embedded human prostate tissue stained for LENG8 using ab230864 at 5 μg/ml in immunohistochemical analysis.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LENG8 antibody (ab230864)
Formalin-fixed, paraffin-embedded human thymus tissue stained for LENG8 using ab230864 at 5 μg/ml in immunohistochemical analysis.
Western blot - Anti-LENG8 antibody (ab230864)
All lanes: Western blot - Anti-LENG8 antibody (ab230864) at 1/1000 dilution
Lane 1: Human fetal heart lysate
Lane 2: Human kidney lysate
Predicted band size: 86 kDa
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com