Rabbit Polyclonal SIM26 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 1 publication.
View Alternative Names
LINC00493, SMIM26, Small integral membrane protein 26
- ICC/IF
Supplier Data
Immunocytochemistry/ Immunofluorescence - Anti-LINC00493 antibody (AB223169)
PFA-fixed, Triton X-100 permeabilized SK-MEL-30 cells stained for LINC00493 (green) using ab223169 at 4 μg/ml in ICC/IF.
Reactivity data
Properties and storage information
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Purification technique
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Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
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Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
LncRNAs such as LINC00493 modulate various gene regulatory processes. LINC00493 functions do not align with classical enzymatic or structural protein roles but instead engage in chromatin remodeling and transcriptional regulation. It often acts in concert with protein complexes such as those involving chromatin-modifying enzymes facilitating modifications of the DNA or histones which affect gene expression patterns significantly.
Pathways
Researchers have linked LINC00493 to transcriptional and epigenetic regulation pathways. In particular LINC00493 interacts with known regulators of the Wnt signaling pathway which is important for cell proliferation and differentiation. The relationship links it to important control of cellular cycles and might interact with proteins such as β-catenin an important player in Wnt signaling indicating a potential role in cell growth and tissue development.
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Publications (1)
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Acta neuropathologica communications 13:164 PubMed40721826
2025
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
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