Rabbit Polyclonal Lipin 1 antibody. Suitable for WB and reacts with Mouse samples. Cited in 6 publications.
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Publications
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- Frontiers in pharmacology 12:7386892021L. Extracts Promote Activity of FXR to Ameliorate Alcoholic Liver Disease: Targeting Liver Lipid Deposition and Inflammation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZhen-Yu Cui,Xin Han,Yu-Chen Jiang,Jia-Yi Dou,Kun-Chen Yao,Zhong-He Hu,Ming-Hui Yuan,Xiao-Xue Bao,Mei-Jie Zhou,Yue Liu,Li-Hua Lian,Xian Zhang,Ji-Xing Nan,Yan-Ling WuPubMed 34690775
- Disease markers 2019:49560162019Diet Alters Serum Metabolomic Profiling in the Mouse Model of Chronic Chagas Cardiomyopathy.Applications:Unspecified applicationReactive species:Unspecified reactive speciesKezia Lizardo et. al.PubMed 31949545
- BioMed research international 2019:51960282019mTORC2 Regulates Lipogenic Gene Expression through PPAR to Control Lipid Synthesis in Bovine Mammary Epithelial Cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZhixin Guo et. al.PubMed 31223619
- International journal of molecular sciences 20:2019Nifedipine Modulates Renal Lipogenesis via the AMPK-SREBP Transcriptional Pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYen-Chung Lin,Mai-Szu Wu,Yuh-Feng Lin,Chang-Rong Chen,Chang-Yu Chen,Chang-Jui Chen,Che-Chou Shen,Kuan-Chou Chen,Chiung-Chi PengPubMed 30934807
- Scientific reports 8:4082018Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury.
- Biochimica et biophysica acta 1841:552-622013Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells.Applications:WBReactive species:Unspecified reactive speciesKai Cai,Natasha C Lucki,Marion B SewerPubMed 24369117
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 98.98% PBS, 1% BSA- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Reactivity data
Select an application| WB | |
|---|---|
| Human | Predicted |
| Mouse | Tested |
| Rat | Predicted |
| Chimpanzee | Predicted |
| Cow | Predicted |
| Dog | Predicted |
| Pig | Predicted |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 1 µg/mL | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Rat, Cow, Dog, Human, Pig, Chimpanzee | Dilution info - | Notes - |
Associated Products
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2 products for Alternative Product
Target data
Function
Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis and therefore controls the metabolism of fatty acids at different levels (PubMed:20231281, PubMed:23426360, PubMed:29765047, PubMed:31695197). Is involved in adipocyte differentiation (By similarity). Recruited at the mitochondrion outer membrane and is involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol (By similarity). Acts also as nuclear transcriptional coactivator for PPARGC1A/PPARA regulatory pathway to modulate lipid metabolism gene expression (By similarity).
Alternative names
KIAA0188, LPIN1, Phosphatidate phosphatase LPIN1, Lipin-1
Recommended products
Rabbit Polyclonal Lipin 1 antibody. Suitable for WB and reacts with Mouse samples. Cited in 6 publications.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 98.98% PBS, 1% BSA- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
Western blot - Anti-Lipin 1 antibody (ab70138)
All lanes: Western blot - Anti-Lipin 1 antibody (ab70138) at 1 µg/mL
Lane 1: Liver (Mouse) Tissue Lysate at 10 µg
Lane 2: Pancreas (Mouse) Tissue Lysate at 10 µg
Lane 3: Kidney (Mouse) Tissue Lysate at 10 µg
SecondaryAll lanes: Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 99 kDa
Observed band size: 110 kDa
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