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AB239731

Anti-Liver Arginase antibody [C5]

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(26 Publications)

Mouse Monoclonal Liver Arginase antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Pig, Human samples. Cited in 26 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human ARG1.

View Alternative Names

Arginase-1, Liver-type arginase, Type I arginase, ARG1

8 Images
Immunocytochemistry/ Immunofluorescence - Anti-Liver Arginase antibody [C5] (AB239731)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-Liver Arginase antibody [C5] (AB239731)

HepG2 (human liver hepatocellular carcinoma cell line) cells stained for Liver Arginase using ab239731 at 40 μg/ml in ICC/IF, followed by FITC staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Liver Arginase antibody [C5] (AB239731)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Liver Arginase antibody [C5] (AB239731)

Paraffin-embedded human liver tissue stained for Liver Arginase using ab239731 at 20 μg/ml in immunohistochemical analysis. DAB staining. HRP-linked Goat anti-Mouse IgG was used as the secondary antibody at 2 μg/ml.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Liver Arginase antibody [C5] (AB239731)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Liver Arginase antibody [C5] (AB239731)

Paraffin-embedded human liver cancer tissue stained for Liver Arginase using ab239731 at 20 μg/ml in immunohistochemical analysis. DAB staining. HRP-linked Goat anti-Mouse IgG was used as the secondary antibody at 2 μg/ml.

Western blot - Anti-Liver Arginase antibody [C5] (AB239731)
  • WB

Supplier Data

Western blot - Anti-Liver Arginase antibody [C5] (AB239731)

All lanes:

Western blot - Anti-Liver Arginase antibody [C5] (ab239731) at 2 µg/mL

All lanes:

Mouse liver lysate

Secondary

All lanes:

HRP-Linked Goat anti-Mouse IgG at 0.2 µg/mL

Predicted band size: 35 kDa

false

Western blot - Anti-Liver Arginase antibody [C5] (AB239731)
  • WB

Supplier Data

Western blot - Anti-Liver Arginase antibody [C5] (AB239731)

All lanes:

Western blot - Anti-Liver Arginase antibody [C5] (ab239731) at 2 µg/mL

All lanes:

HepG2 (human liver hepatocellular carcinoma cell line) cell lysate

Secondary

All lanes:

HRP-Linked goat anti-Mouse IgG at 0.2 µg/mL

Predicted band size: 35 kDa

false

Western blot - Anti-Liver Arginase antibody [C5] (AB239731)
  • WB

Supplier Data

Western blot - Anti-Liver Arginase antibody [C5] (AB239731)

All lanes:

Western blot - Anti-Liver Arginase antibody [C5] (ab239731) at 2 µg/mL

All lanes:

Pig liver lysate

Secondary

All lanes:

HRP-Linked Goat anti-Mouse IgG at 0.2 µg/mL

Predicted band size: 35 kDa

false

Western blot - Anti-Liver Arginase antibody [C5] (AB239731)
  • WB

Supplier Data

Western blot - Anti-Liver Arginase antibody [C5] (AB239731)

All lanes:

Western blot - Anti-Liver Arginase antibody [C5] (ab239731) at 2 µg/mL

All lanes:

Human liver lysate

Secondary

All lanes:

HRP-Linked goat anti-Mouse IgG at 0.2 µg/mL

Predicted band size: 35 kDa

false

Western blot - Anti-Liver Arginase antibody [C5] (AB239731)
  • WB

Supplier Data

Western blot - Anti-Liver Arginase antibody [C5] (AB239731)

All lanes:

Western blot - Anti-Liver Arginase antibody [C5] (ab239731) at 5 µg/mL

All lanes:

Recombinant human Liver Arginase protein

Predicted band size: 35 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

C5

Isotype

IgG2b

Light chain type

kappa

Carrier free

No

Reacts with

Mouse, Human, Pig

Applications

IHC-P, ICC/IF, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human ARG1.

P05089

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-30 µg/mL", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "5-30 µg/mL", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Pig": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rabbit": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A/G
Purification notes
Purified from TCS.
Storage buffer
pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.. Functions in L-arginine homeostasis in nonhepatic tissues characterized by the competition between nitric oxide synthase (NOS) and arginase for the available intracellular substrate arginine. Arginine metabolism is a critical regulator of innate and adaptive immune responses. Involved in an antimicrobial effector pathway in polymorphonuclear granulocytes (PMN). Upon PMN cell death is liberated from the phagolysosome and depletes arginine in the microenvironment leading to suppressed T cell and natural killer (NK) cell proliferation and cytokine secretion (PubMed : 15546957, PubMed : 16709924, PubMed : 19380772). In group 2 innate lymphoid cells (ILC2s) promotes acute type 2 inflammation in the lung and is involved in optimal ILC2 proliferation but not survival (By similarity). In humans, the immunological role in the monocytic/macrophage/dendritic cell (DC) lineage is unsure.
See full target information ARG1
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Publications (26)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in aging neuroscience 17:1555067 PubMed40842649

2025

Ginsenoside Rb1 attenuates neuroflammation via activating Wnt/β-catenin signaling pathway to exert neuroprotective effect on cerebral ischemic-reperfusion injury.

Applications

Unspecified application

Species

Unspecified reactive species

Ruo-Jing Liu,Xue Zhao,Yi-Zhen Zhu,Ling-Ling Fu,Guo Ge,Jun-de Zhu

Drug design, development and therapy 19:4755-4776 PubMed40486123

2025

Alleviates Th17/Treg Immune Imbalance of Experimental Autoimmune Encephalomyelitis by Regulating the Fatty Acids Metabolism.

Applications

Unspecified application

Species

Unspecified reactive species

Lulu Wu,Haoyou Xu,Hui Xia,Lilin Peng,Lulu Qin,Qian Gong,Min Zhao,Zhibing Wu,Yuanqi Zhao,Zequan Zheng

Stem cell research & therapy 16:161 PubMed40165226

2025

Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia.

Applications

Unspecified application

Species

Unspecified reactive species

Yonghao Liu,Heng Zhou,Pengcheng Pang,Ye Liu,Jieying Situ,Junnan Wang,Yan He,Qingsong Ye

Materials today. Bio 30:101392 PubMed39759850

2025

Construction and high-throughput screening of gradient nanowire coatings on titanium surface towards ameliorated osseointegration.

Applications

Unspecified application

Species

Unspecified reactive species

Ruiyue Hang,Yuyu Zhao,Huanming Chen,Xiaomei Li,Runhua Yao,Yonghua Sun,Xiaohong Yao,Long Bai,Huaiyu Wang,Yong Han,Ruiqiang Hang

Molecular medicine (Cambridge, Mass.) 30:283 PubMed39736512

2024

Thioredoxin-interacting protein (TXNIP) inhibition promotes retinal ganglion cell survival and facilitates M1-like microglial transformation via the PI3K/Akt pathway in glaucoma.

Applications

Unspecified application

Species

Unspecified reactive species

Junjue Chen,Huimin Zhong,Bingqiao Shen,Huan Yu,Yang Zhang,Ruiqi Han,Ping Huang,Shouyue Huang,Yisheng Zhong

Biomolecules 14: PubMed39595610

2024

Evaluation of the Efficacy of a Full-Spectrum Low-THC Plant Extract Using In Vitro Models of Inflammation and Excitotoxicity.

Applications

Unspecified application

Species

Unspecified reactive species

Emily Ross-Munro,Esra Isikgel,Bobbi Fleiss

Neural regeneration research 20:2611-2623 PubMed39314167

2024

High-dose dexamethasone regulates microglial polarization via the GR/JAK1/STAT3 signaling pathway after traumatic brain injury.

Applications

Unspecified application

Species

Unspecified reactive species

Mengshi Yang,Miao Bai,Yuan Zhuang,Shenghua Lu,Qianqian Ge,Hao Li,Yu Deng,Hongbin Wu,Xiaojian Xu,Fei Niu,Xinlong Dong,Bin Zhang,Baiyun Liu

Redox biology 76:103318 PubMed39178733

2024

ALDH2 deficiency augments atherosclerosis through the USP14-cGAS-dependent polarization of proinflammatory macrophages.

Applications

Unspecified application

Species

Unspecified reactive species

Haiying Rui,Huaxiang Yu,Kai Chi,Ziqi Han,Wenyong Zhu,Jian Zhang,Haipeng Guo,Wenyi Zou,Fengxin Wang,Ping Xu,Dan Zou,Xiaoshuai Song,Lulu Liu,Xuting Wu,Wenxiao Wu,Dandan Qin,Yihai Cao,Feng Xu,Li Xue,Yuguo Chen

Journal of nanobiotechnology 22:351 PubMed38902789

2024

Repair spinal cord injury with a versatile anti-oxidant and neural regenerative nanoplatform.

Applications

Unspecified application

Species

Unspecified reactive species

Heng Zhou,Ziwei Li,Shuili Jing,Ben Wang,Zhifei Ye,Wei Xiong,Yonghao Liu,Ye Liu,Chun Xu,Tushar Kumeria,Yan He,Qingsong Ye

Bioactive materials 40:19-33 PubMed38882001

2024

L-arginine loading porous PEEK promotes percutaneous tissue repair through macrophage orchestration.

Applications

Unspecified application

Species

Unspecified reactive species

Tong Zhao,Xingdan Liu,Zhuangzhuang Chu,Jing Zhao,Dongya Jiang,Xiaohua Dong,Ziyi Lu,Kelvin W K Yeung,Xuanyong Liu,Liping Ouyang
View all publications
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