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AB249715

Anti-LMTK2 antibody [EPR7836(2)] - BSA and Azide free

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Rabbit Recombinant Monoclonal LMTK2 antibody. Carrier free. Suitable for IHC-P, WB and reacts with Human samples.

View Alternative Names

AATYK2, BREK, KIAA1079, KPI2, LMR2, LMTK2, Serine/threonine-protein kinase LMTK2, Apoptosis-associated tyrosine kinase 2, Brain-enriched kinase, CDK5/p35-regulated kinase, Kinase/phosphatase/inhibitor 2, Lemur tyrosine kinase 2, Serine/threonine-protein kinase KPI-2, hBREK, CPRK

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LMTK2 antibody [EPR7836(2)] - BSA and Azide free (AB249715)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LMTK2 antibody [EPR7836(2)] - BSA and Azide free (AB249715)

This data was developed using ab172622, the same antibody clone in a different buffer formulation.

Immunohistochemical analysis of paraffin-embedded Human skeletal muscle tissue labeling LMTK2 with ab172622 at 1/100 dilution.

Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Western blot - Anti-LMTK2 antibody [EPR7836(2)] - BSA and Azide free (AB249715)
  • WB

Supplier Data

Western blot - Anti-LMTK2 antibody [EPR7836(2)] - BSA and Azide free (AB249715)

This data was developed using ab172622, the same antibody clone in a different buffer formulation.

All lanes:

Western blot - Anti-LMTK2 antibody [EPR7836(2)] (<a href='/en-us/products/primary-antibodies/lmtk2-antibody-epr78362-ab172622'>ab172622</a>) at 1/1000 dilution

All lanes:

Human skeletal muscle lysate at 10 µg

Predicted band size: 164 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR7836(2)

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Primary Antibodies

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Primary Antibodies

AB134988

Anti-CPT1B antibody

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" }, "Mouse": { "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" }, "Rat": { "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
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Product details

ab249715 is the carrier-free version of ab172622.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Compatibility
This product is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar® is a trademark of Fluidigm Canada Inc.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Storage buffer
pH: 7.2 - 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The LMTK2 protein also known as Lemur Tyrosine Kinase 2 is a serine/threonine kinase with an approximated mass of 150 kDa. It plays an important role in protein phosphorylation influencing various cellular processes. LMTK2 is expressed in multiple tissues notably in the brain and testis. Its kinase activity impacts neurodevelopment and spermatogenesis reflecting its significant presence in these areas.
Biological function summary

LMTK2 influences neuron maintenance and signaling. It is not known to be part of any large protein complex but interacts closely with important cellular proteins. LMTK2 has a regulatory effect on axonal outgrowth and synaptic vesicle transport which are essential for neuron function. Moreover it interacts with other kinases and phosphatases impacting cellular signal transduction pathways.

Pathways

LMTK2 has important roles in the Wnt and MAPK signaling pathways. Within the Wnt pathway LMTK2 modulates cellular growth and differentiation by interacting with proteins like beta-catenin. In the MAPK pathway its influence on kinases helps control cell proliferation and stress responses. The interactions of LMTK2 with these signaling pathways highlight its influence on cell fate decisions and adaptive responses.

LMTK2 associates with neurodegenerative diseases and cancer. Its dysfunction has been linked to Alzheimer's disease where aberrant signaling affects neuronal health. LMTK2 potentially interacts with tau protein impacting tau pathology. In cancer altered LMTK2 expression associates with disrupted cellular growth signaling suggesting a role in tumor progression. Understanding these connections offers insights for therapeutic innovations.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Phosphorylates PPP1C, phosphorylase b and CFTR.
See full target information LMTK2
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com