AB137533

Anti-Loricrin antibody

Name: Anti-Loricrin antibody (ab137533) | Abcam
Brand: Abcam Limited
SKU: AB137533
Price: 535 USD
Availability: InStock

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(6 Publications)

Rabbit Polyclonal Loricrin antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Human LORICRIN aa 1-50.

View Alternative Names

LOR, LRN, LORICRIN, Loricrin

2 Images

Immunocytochemistry/ Immunofluorescence - Anti-Loricrin antibody (AB137533)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-Loricrin antibody (AB137533)

Immunofluorescence analysis of methanol fixed Hep3B cells labelling Loricrin with ab137533 at 1/500. The lower panel shows costaing with Hoechst 33342.

Supplier Data

Western blot - Anti-Loricrin antibody (AB137533)

Samples were separated by 12 % SDS.

All lanes:

Western blot - Anti-Loricrin antibody (ab137533) at 1/1000 dilution

All lanes:

HeLa Whole cell extract at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 26 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

ICC/IF, WB

applications

Immunogen

Synthetic Peptide within Human LORICRIN aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

P23490

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/1000", "ICCIF-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Major keratinocyte cell envelope protein.

See full target information LORICRIN

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Cells 13: PubMed39682709

2024

Impairment of Intermediate Filament Expression Reveals Impact on Cell Functions Independent from Keratinocyte Transformation.

Applications

Unspecified application

Species

Unspecified reactive species

Charlotte Klein,Imke Ramminger,Shuoqiu Bai,Thorsten Steinberg,Pascal Tomakidi

Carcinogenesis 45:436-449 PubMed38470060

2024

Growth modulatory effects of fenretinide encompass keratinocyte terminal differentiation: a favorable outcome for oral squamous cell carcinoma chemoprevention.

Applications

Unspecified application

Species

Unspecified reactive species

Daren Wang,Ping Pei,Fortune Shea,Richard Spinney,Albert Chang,Joerg Lahann,Susan R Mallery

Aging 13:18392-18403 PubMed34314383

2021

Curcumol may alleviate psoriasis-like inflammation by inhibiting keratinocyte proliferation and inflammatory gene expression via JAK1/STAT3 signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Mingfen Lv,Junyi Shao,Fan Jiang,Jingjing Liu

Molecular medicine reports 24: PubMed34278486

2021

Cinnamaldehyde inhibits psoriasis‑like inflammation by suppressing proliferation and inflammatory response of keratinocytes via inhibition of NF‑κB and JNK signaling pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Zhenzhen Ding,Jingjing Liu,Huangjing Qian,Lingjian Wu,Mingfen Lv

Neoplasia (New York, N.Y.) 23:1-11 PubMed33190089

2020

CBP-mediated Wnt3a/β-catenin signaling promotes cervical oncogenesis initiated by Piwil2.

Applications

Unspecified application

Species

Unspecified reactive species

Dingqing Feng,Keqin Yan,Haiyan Liang,Jing Liang,Wenhui Wang,Huan Yu,Ying Zhou,Weidong Zhao,Zhongjun Dong,Bin Ling

Molecular biology of the cell 25:2882-90 PubMed25057011

2014

Nuclear factor of activated T-cells 5 increases intestinal goblet cell differentiation through an mTOR/Notch signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Yuning Zhou,Qingding Wang,Heidi L Weiss,B Mark Evers

View all publications

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