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AB198994

Anti-Loricrin antibody [EPR7149(2)] - C-terminal

5

(3 Reviews)

|

(14 Publications)

Anti-Loricrin antibody [EPR7149(2)] - C-terminal (ab198994) is a rabbit monoclonal antibody detecting Loricrin in IHC-P, ICC/IF. Suitable for Human, Rat.

- Biophysical QC for unrivalled batch-batch consistency

View Alternative Names

LOR, LRN, LORICRIN, Loricrin

4 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Loricrin antibody [EPR7149(2)] - C-terminal (AB198994)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Loricrin antibody [EPR7149(2)] - C-terminal (AB198994)

Immunohistochemical analysis of paraffin-embedded human uterus tissue sections labeling Loricrin with ab198994 at a 1/500 dilution. Goat anti-rabbit IgG H&L (HRP) ab97051 used as the secondary at a 1/500 dilution. Counterstain hematoxylin. Used as a negative tissue control.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Immunocytochemistry/ Immunofluorescence - Anti-Loricrin antibody [EPR7149(2)] - C-terminal (AB198994)
  • ICC/IF

Lab

Immunocytochemistry/ Immunofluorescence - Anti-Loricrin antibody [EPR7149(2)] - C-terminal (AB198994)

Immunocytochemistry/ Immunofluorescence analysis of A431 cell line labeling Loricrin with ab198994 at a 1/250 dilution. Cells were fixed with 4% paraformaldehyde and permeabilized using 0.1% Triton X-100. Alexa Fluor® 488 Goat anti-Rabbit ab150077 used as the secondary at a 1/1000 dilution. Counterstained using ab7291 anti-Tubulin (mouse mAb) at a 1/1000 dilution and ab150120 Alexa Fluor® 594 Goat anti-Mouse secondary at a 1/500 dilution.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Loricrin antibody [EPR7149(2)] - C-terminal (AB198994)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Loricrin antibody [EPR7149(2)] - C-terminal (AB198994)

Immunohistochemical analysis of paraffin-embedded human skin tissue sections labeling Loricrin with ab198994 at a 1/500 dilution. Goat anti-rabbit IgG H&L (HRP) ab97051 used as the secondary at a 1/500 dilution. Counterstain hematoxylin.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Loricrin antibody [EPR7149(2)] - C-terminal (AB198994)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Loricrin antibody [EPR7149(2)] - C-terminal (AB198994)

Immunohistochemical analysis of paraffin-embedded rat skin tissue sections labeling Loricrin with ab198994 at a 1/500 dilution. Goat anti-rabbit IgG H&L (HRP) ab97051 used as the secondary at a 1/500 dilution. Counterstain hematoxylin.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

  • Carrier free

    Anti-Loricrin antibody [EPR7149(2)] - BSA and Azide free

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-Loricrin antibody [EPR7149(2)] – C–terminal

  • 578 PE

    PE Anti-Loricrin antibody [EPR7149(2)] – C–terminal

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-Loricrin antibody [EPR7149(2)] – C–terminal

  • 617 Alexa Fluor® 594

    Alexa Fluor® 594 Anti-Loricrin antibody [EPR7149(2)] – C–terminal

  • 660 APC

    APC Anti-Loricrin antibody [EPR7149(2)] – C–terminal

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-Loricrin antibody [EPR7149(2)] – C–terminal

  • 775 Alexa Fluor® 750

    Alexa Fluor® 750 Anti-Loricrin antibody [EPR7149(2)] - C-terminal

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR7149(2)

Isotype

IgG

Carrier free

No

Reacts with

Rat, Human

Applications

IHC-P, ICC/IF

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/250", "ICCIF-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/250", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol." }, "Rat": { "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/250", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol." } } }
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Product details

What is this antibody validated in?
Anti-Loricrin antibody [EPR7149(2)] - C-terminal (ab198994) is a rabbit recombinant monoclonal antibody and is validated for use in Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Rat samples.

Trial sizes available!
Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies.

Other related products
We have a range of other formats of antibody clone [EPR7149(2)] also available for your convenience: ab198994, Carrier free - ab240345, APC - ab319260, PE - ab319408, Alexa Fluor® 488 - ab319542, Alexa Fluor® 647 - ab319655, Alexa Fluor® 594 - ab319759, Alexa Fluor® 555 - ab319901, Alexa Fluor® 750 - ab321343

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Major keratinocyte cell envelope protein.
See full target information LORICRIN
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Publications (14)

Recent publications for all applications. Explore the full list and refine your search

Journal of cellular and molecular medicine 29:e70800 PubMed40845179

2025

Decoy Receptor 2 as a Cell Cycle Arrest Biomarker for Predicting Renal Recovery Following Acute Kidney Injury.

Applications

Unspecified application

Species

Unspecified reactive species

Xiangling Yi,Liming Wang,Xiao-Yue Wang,Yu Fang,Jiarui Liu,Kehong Chen,Ya-Ni He,Jia Chen

Biology 14: PubMed40136522

2025

A Triple-Precursor Blend as a Topical Solution to Protect the Skin Against Environmental Damage.

Applications

Unspecified application

Species

Unspecified reactive species

Ping Gao,Xue Xiao,Zhuang Zhou,Hong Zhang,Raghupathi Subramanian,Anuchai Sinsawat,Xuelan Gu

Journal of tissue engineering 16:20417314241312511 PubMed39917589

2025

Dissolving microneedle patch loaded with adipokines-enriched adipose extract relieves atopic dermatitis in mouse via modulating immune disorders, microbiota imbalance, and skin barrier defects.

Applications

Unspecified application

Species

Unspecified reactive species

Jingyan Guan,Kaiqi Chen,Feng Lu,Yunfan He

Biofabrication 16: PubMed38941996

2024

A biopsy-sized 3D skin model with a perifollicular vascular plexus enables studying immune cell trafficking in the skin.

Applications

Unspecified application

Species

Unspecified reactive species

Krutav Rakesh Shah,Laura Garriga-Cerda,Alberto Pappalardo,Leila Sorrells,Hun Jin Jeong,Chang H Lee,Hasan Erbil Abaci

Cell death & disease 15:392 PubMed38834617

2024

FBP1 orchestrates keratinocyte proliferation/differentiation and suppresses psoriasis through metabolic control of histone acetylation.

Applications

Unspecified application

Species

Unspecified reactive species

Pengfei Zhang,Ju Yang,Xiong Liu,Congshu Huang,Yuandong Tao,Pan Shen,Zhijie Bai,Chengrong Xiao,Lei Zhou,Gaofu Li,Li Zhang,Wei Zhou,Yue Gao

Cell proliferation 56:e13441 PubMed36919255

2023

Zonula occludens-1 distribution and barrier functions are affected by epithelial proliferation and turnover rates.

Applications

Unspecified application

Species

Unspecified reactive species

Keisuke Imafuku,Hiroaki Iwata,Ken Natsuga,Makoto Okumura,Yasuaki Kobayashi,Hiroyuki Kitahata,Akiharu Kubo,Masaharu Nagayama,Hideyuki Ujiie

Science advances 9:eade2514 PubMed36706190

2023

Engineering edgeless human skin with enhanced biomechanical properties.

Applications

Unspecified application

Species

Unspecified reactive species

Alberto Pappalardo,David Alvarez Cespedes,Shuyang Fang,Abigail R Herschman,Eun Young Jeon,Kristin M Myers,Jeffrey W Kysar,Hasan Erbil Abaci

International journal of molecular sciences 23: PubMed36361668

2022

An Inflamed and Infected Reconstructed Human Epidermis to Study Atopic Dermatitis and Skin Care Ingredients.

Applications

Unspecified application

Species

Unspecified reactive species

Sébastien Cadau,Manon Gault,Nicolas Berthelemy,Chiung-Yueh Hsu,Louis Danoux,Nicolas Pelletier,Dominique Goudounèche,Carole Pons,Corinne Leprince,Valérie André-Frei,Michel Simon,Sabine Pain

Experimental dermatology 32:30-40 PubMed36134503

2022

RNA sequencing reveals the transcriptome profile of the atopic prurigo nodularis with severe itching.

Applications

Unspecified application

Species

Unspecified reactive species

Yixin Shao,Yiqi Zhu,Zijing Xiao,Yanyun Shen,Beiying Dai,Hui Tang,Duoqin Wang

Stem cells (Dayton, Ohio) 40:435-445 PubMed35325240

2022

CDK12 Is Necessary to Promote Epidermal Differentiation Through Transcription Elongation.

Applications

Unspecified application

Species

Unspecified reactive species

Jingting Li,Manisha Tiwari,Yifang Chen,Sudjit Luanpitpong,George L Sen
View all publications
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Product promise

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