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AB232884

Anti-LOXL3 antibody

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(2 Publications)

Rabbit Polyclonal LOXL3 antibody. Suitable for WB, IHC-P and reacts with Mouse samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Mouse Loxl3 aa 500-750.

View Alternative Names

Lor2, Loxl3, Lysyl oxidase homolog 3, Lysyl oxidase-like protein 3, Lysyl oxidase-related protein 2

6 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)

Formalin-fixed, paraffin-embedded mouse lung tissue stained for LOXL3 with ab232884 at 20 μg/ml in immunohistochemical analysis.

Secondary used : HRP-Linked Goat anti-Rabbit IgG polyclonal at 2 μg/ml. DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)

Formalin-fixed, paraffin-embedded mouse spleen tissue stained for LOXL3 with ab232884 at 20 μg/ml in immunohistochemical analysis.

Secondary used : HRP-Linked Goat anti-Rabbit IgG polyclonal at 2 μg/ml. DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)

Formalin-fixed, paraffin-embedded mouse pancreas tissue stained for LOXL3 with ab232884 at 20 μg/ml in immunohistochemical analysis.

Secondary used : HRP-Linked Goat anti-Rabbit IgG polyclonal at 2 μg/ml. DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)

Formalin-fixed, paraffin-embedded mouse cerebrum tissue stained for LOXL3 with ab232884 at 20 μg/ml in immunohistochemical analysis.

Secondary used : HRP-Linked Goat anti-Rabbit IgG polyclonal at 2 μg/ml. DAB staining.

Western blot - Anti-LOXL3 antibody (AB232884)
  • WB

Supplier Data

Western blot - Anti-LOXL3 antibody (AB232884)

All lanes:

Western blot - Anti-LOXL3 antibody (ab232884) at 3 µg/mL

All lanes:

Mouse serum

Secondary

All lanes:

HRP-linked Guinea pig anti-Rabbit at 1/2000 dilution

Predicted band size: 83 kDa

false

Western blot - Anti-LOXL3 antibody (AB232884)
  • WB

Supplier Data

Western blot - Anti-LOXL3 antibody (AB232884)

All lanes:

Western blot - Anti-LOXL3 antibody (ab232884) at 2 µg/mL

All lanes:

Recombinant mouse LOXL3 protein

Predicted band size: 83 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Mouse Loxl3 aa 500-750. The exact immunogen used to generate this antibody is proprietary information.

Q9Z175

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-2 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Purification notes
Antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Protein-lysine 6-oxidase that mediates the oxidation of peptidyl lysine residues to allysine in target proteins (PubMed : 26954549). Catalyzes the post-translational oxidative deamination of peptidyl lysine residues in precursors of elastin and different types of collagens, a prerequisite in the formation of cross-links between collagens and elastin (PubMed : 26307084). Required for somite boundary formation by catalyzing oxidation of fibronectin (FN1), enhancing integrin signaling in myofibers and their adhesion to the myotendinous junction (MTJ) (PubMed : 26954549). Acts as a regulator of inflammatory response by inhibiting differentiation of naive CD4(+) T-cells into T-helper Th17 or regulatory T-cells (Treg) : acts by interacting with STAT3 in the nucleus and catalyzing both deacetylation and oxidation of lysine residues on STAT3, leading to disrupt STAT3 dimerization and inhibit STAT3 transcription activity (PubMed : 28065600). Oxidation of lysine residues to allysine on STAT3 preferentially takes place on lysine residues that are acetylated (By similarity). Also able to catalyze deacetylation of lysine residues on STAT3 (By similarity).
See full target information Loxl3
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Environmental toxicology 37:2540-2551 PubMed35841383

2022

LOXL3-promoted hepatocellular carcinoma progression via promotion of Snail1/USP4-mediated epithelial-mesenchymal transition.

Applications

Unspecified application

Species

Unspecified reactive species

Rong Li,Runze Shang,Shunle Li,Yifan Ren,Lin Shen,Longbao Yang,Shuo Chen,Xi Chen,Junhui Li,Meng Xu

PLoS genetics 15:e1008196 PubMed31173582

2019

Cyclophilin B control of lysine post-translational modifications of skin type I collagen.

Applications

Unspecified application

Species

Unspecified reactive species

Masahiko Terajima,Yuki Taga,Wayne A Cabral,Ying Liu,Masako Nagasawa,Noriko Sumida,Yukako Kayashima,Prashant Chandrasekaran,Lin Han,Nobuyo Maeda,Irina Perdivara,Shunji Hattori,Joan C Marini,Mitsuo Yamauchi
View all publications
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