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AB183076

Anti-LPA-4 antibody

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(4 Publications)

Rabbit Polyclonal LPA-4 antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human LPAR4 aa 350 to C-terminus.

View Alternative Names

GPR23, LPA4, P2RY9, LPAR4, Lysophosphatidic acid receptor 4, LPA receptor 4, LPA-4, G-protein coupled receptor 23, P2Y purinoceptor 9, P2Y5-like receptor, Purinergic receptor 9, P2Y9

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LPA-4 antibody (AB183076)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LPA-4 antibody (AB183076)

Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue labeling LPA-4 with ab183076 at a 1/30 dilution, in the presence (right panel) or absence (left panel) of immunizing peptide. (Original magnification : ×200)

Western blot - Anti-LPA-4 antibody (AB183076)
  • WB

Supplier Data

Western blot - Anti-LPA-4 antibody (AB183076)

10%SDS-PAGE

All lanes:

Western blot - Anti-LPA-4 antibody (ab183076) at 1/450 dilution

Lane 1:

Human leiomyosarcoma tissue lysate at 40 µg

Lane 2:

Human liver cancer tissue lysate at 40 µg

Secondary

All lanes:

Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution

Predicted band size: 42 kDa

true

Exposure time: 30s

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Synthetic Peptide within Human LPAR4 aa 350 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q99677

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/25 - 1/100", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/450 - 1/2000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1-alkyl- > 1-alkenyl-LPA.
See full target information LPAR4
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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Pharmaceuticals (Basel, Switzerland) 17: PubMed38399439

2024

Arnicolide C Suppresses Tumor Progression by Targeting 14-3-3θ in Breast Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Zhengrui Liu,Xiaodan Lyu,Jiaxu Chen,Benteng Zhang,Siman Xie,Yan Yuan,Li Sun,Shengtao Yuan,Hong Yu,Jian Ding,Mei Yang

Frontiers in endocrinology 13:896558 PubMed35903269

2022

Lysophosphatidic Acid Improves Human Sperm Motility by Enhancing Glycolysis and Activating L-Type Calcium Channels.

Applications

Unspecified application

Species

Unspecified reactive species

Yinlam Li,Li Jin,Yanquan Li,Jianing Qian,Zhengquan Wang,Xiaoguo Zheng,Chong Xie,Xuelian Zhang,Hefeng Huang,Yuchuan Zhou

The Journal of clinical investigation 130:1513-1526 PubMed32065590

2020

Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney.

Applications

Unspecified application

Species

Unspecified reactive species

Petra Simic,Wondong Kim,Wen Zhou,Kerry A Pierce,Wenhan Chang,David B Sykes,Najihah B Aziz,Sammy Elmariah,Debby Ngo,Paola Divieti Pajevic,Nicolas Govea,Bryan R Kestenbaum,Ian H de Boer,Zhiqiang Cheng,Marta Christov,Jerold Chun,David E Leaf,Sushrut S Waikar,Andrew M Tager,Robert E Gerszten,Ravi I Thadhani,Clary B Clish,Harald Jüppner,Marc N Wein,Eugene P Rhee

Journal of cellular biochemistry 119:6429-6441 PubMed29240250

2018

Microrna-139-5p inhibits epithelial-mesenchymal transition and fibrosis in post-menopausal women with interstitial cystitis by targeting LPAR4 via the PI3K/Akt signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Chen Jiang,Zhen Tong,Wei-Lin Fang,Qi-Bo Fu,Yin-Jun Gu,Ting-Ting Lv,Dong-Ming Liu,Wei Xue,Jian-Wei Lv
View all publications
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