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AB137304

Anti-LRAT antibody

0

(1 Review)

|

(2 Publications)

Rabbit Polyclonal LRAT antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human LRAT.

View Alternative Names

Lecithin retinol acyltransferase, Phosphatidylcholine--retinol O-acyltransferase, LRAT

1 Images
Western blot - Anti-LRAT antibody (AB137304)
  • WB

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Western blot - Anti-LRAT antibody (AB137304)

All lanes:

Western blot - Anti-LRAT antibody (ab137304) at 1/500 dilution

All lanes:

COLO205 cell lysate at 30 µg

Predicted band size: 26 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human LRAT. The exact immunogen used to generate this antibody is proprietary information.

O95237

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
ab137304 was affinity purified from Rabbit antiserum by affinity chromatography using epitope specific peptide.
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters (PubMed : 9920938). Retinyl esters are storage forms of vitamin A (Probable). LRAT plays a critical role in vision (Probable). It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments (Probable). Required for the survival of cone photoreceptors and correct rod photoreceptor cell morphology (By similarity).
See full target information LRAT
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Molecular vision 23:60-89 PubMed28356702

2017

Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells.

Applications

WB

Species

Human

William Samuel,Cynthia Jaworski,Olga A Postnikova,R Krishnan Kutty,Todd Duncan,Li Xuan Tan,Eugenia Poliakov,Aparna Lakkaraju,T Michael Redmond

Investigative ophthalmology & visual science 55:198-209 PubMed24255038

2014

Retinoid uptake, processing, and secretion in human iPS-RPE support the visual cycle.

Applications

Unspecified application

Species

Unspecified reactive species

Alberto Muñiz,Whitney A Greene,Mark L Plamper,Jae Hyek Choi,Anthony J Johnson,Andrew T Tsin,Heuy-Ching Wang
View all publications
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Product promise

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