Rabbit Polyclonal LRAT antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human LRAT.
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- Frontiers in bioengineering and biotechnology 8:4562020Optimisation of a Novel Bio-Substrate as a Treatment for Atrophic Age-Related Macular Degeneration.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRachel McCormick et. al.PubMed 32500067
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS, 0.88% Sodium chloride- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human LRAT. The exact immunogen used to generate this antibody is proprietary information. Database link O95237
Reactivity data
Select an application| WB | IHC-P | ICC/IF | |
|---|---|---|---|
| Human | Tested | Tested | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500.00000 - 1/1000.00000 | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 5 µg/mL | Notes - |
ICC/IF
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/100.00000 - 1/500.00000 | Notes - |
Associated Products
Select an associated product type
1 product for Alternative Product
Target data
Function
Transfers the acyl group from the sn-1 position of phosphatidylcholine to all-trans retinol, producing all-trans retinyl esters (PubMed:9920938). Retinyl esters are storage forms of vitamin A (Probable). LRAT plays a critical role in vision (Probable). It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase, 11 cis-retinol is oxidized and converted into 11-cis-retinaldehyde which is the chromophore for rhodopsin and the cone photopigments (Probable). Required for the survival of cone photoreceptors and correct rod photoreceptor cell morphology (By similarity).
Alternative names
Lecithin retinol acyltransferase, Phosphatidylcholine--retinol O-acyltransferase, LRAT
Recommended products
Rabbit Polyclonal LRAT antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human LRAT.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS, 0.88% Sodium chloride- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human LRAT. The exact immunogen used to generate this antibody is proprietary information. Database link O95237
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
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3 product images
Western blot - Anti-LRAT antibody (ab166784)
All lanes: Western blot - Anti-LRAT antibody (ab166784) at 1/500 dilution
Lane 1: COLO205 cell extract
Lane 2: COLO205 cell extract with immunizing peptide
Predicted band size: 26 kDa
Immunocytochemistry/ Immunofluorescence - Anti-LRAT antibody (ab166784)
Immunofluorescent analysis of HUVEC cells labeling LRAT with ab166784 at 1/100 dilution in the presence (right panel) or absence (left panel) of immunizing peptide.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LRAT antibody (ab166784)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human tonsil tissue labeling LRAT with ab166784 at 5 µg/ml.
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