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AB221772

Anti-LRR-1 antibody

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(1 Publication)

Rabbit Polyclonal LRR-1 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human LRR1 aa 250-350.

View Alternative Names

PPIL5, LRR1, Leucine-rich repeat protein 1, 4-1BB-mediated-signaling molecule, 4-1BBlrr, LRR-repeat protein 1, Peptidylprolyl isomerase-like 5, LRR-1

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-LRR-1 antibody (AB221772)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-LRR-1 antibody (AB221772)

PFA-fixed, Triton X-100 permeabilized PC-3 (human prostate adenocarcinoma cell line) cells stained for LRR-1 (green) using ab221772 at 4 μg/ml in ICC/IF.

Western blot - Anti-LRR-1 antibody (AB221772)
  • WB

Supplier Data

Western blot - Anti-LRR-1 antibody (AB221772)

Western blot analysis of human testis tissue lysate with ab221772 at 0.4 μg/ml.

All lanes:

Western blot - Anti-LRR-1 antibody (ab221772) at 0.4 µg/mL

Predicted band size: 47 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human LRR1 aa 250-350. The exact immunogen used to generate this antibody is proprietary information.

Q96L50

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Substrate recognition subunit of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed : 15601820). ECS(LRR1) ubiquitinates MCM7 and promotes CMG replisome disassembly by VCP and chromatin extraction during S-phase (By similarity). May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1 (PubMed : 11804328).
See full target information LRR1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

iScience 27:110651 PubMed39262789

2024

Knockouts of , , or from cholesterol synthesis reveal pathways modulated by sterol intermediates.

Applications

Unspecified application

Species

Unspecified reactive species

Cene Skubic,Hana Trček,Petra Nassib,Tinkara Kreft,Andrew Walakira,Katka Pohar,Sara Petek,Tadeja Režen,Alojz Ihan,Damjana Rozman
View all publications
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Product promise

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