Anti-LRRC4C antibody

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

The LRRC4C protein also known as SRR3 or Leucine Rich Repeat Containing 4C plays a role in neuronal signaling. This protein weighs approximately 83 kDa and shows expression predominantly in the nervous system especially in brain tissue. LRRC4C belongs to a family known for containing leucine-rich repeats which are structures involved in protein-protein interactions.

Biological function summary

LRRC4C influences neuronal synapse development and functioning. It interacts with other synaptic components and may form part of larger molecular complexes at the synapse. Its expression and function suggest it might affect synapse formation stabilization and plasticity important for effective neuronal communication and network stabilization.

Pathways

LRRC4C participates in processes involved in synaptic signaling pathways. It closely interacts with proteins such as neuroligins which are important for synaptic adhesion and communication between neurons. These pathways are essential in maintaining the structure and function of synapses contributing to both neuronal growth and signaling efficiency.

Associated diseases and disorders

LRRC4C shows potential connections to neurological conditions such as autism spectrum disorder and schizophrenia. Studies suggest that its interaction with proteins like neurexins might influence disease pathogenesis given their roles in synaptic organization and function. Disruptions in these pathways can lead to synaptic imbalances contributing to the symptoms associated with these disorders.