JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB234654

Anti-Lysozyme C-1 antibody

Be the first to review this product! Submit a review

|

(1 Publication)

Rabbit Polyclonal Lysozyme C-1 antibody. Suitable for WB and reacts with Recombinant full length protein - Duck samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Duck Lysozyme C-1.

View Alternative Names

Lysozyme C-1

1 Images
Western blot - Anti-Lysozyme C-1 antibody (AB234654)
  • WB

Supplier Data

Western blot - Anti-Lysozyme C-1 antibody (AB234654)

All lanes:

Western blot - Anti-Lysozyme C-1 antibody (ab234654) at 1/500 dilution

Lane 1:

Recombinant Anas platyrhynchos Lysozyme C-1 protein, 80 ng

Lane 2:

Recombinant Anas platyrhynchos Lysozyme C-1 protein, 40 ng

Lane 3:

Recombinant Anas platyrhynchos Lysozyme C-1 protein, 20 ng

Lane 4:

Recombinant Anas platyrhynchos Lysozyme C-1 protein, 10 ng

Secondary

All lanes:

Goat polyclonal to rabbit IgG at 1/50000 dilution

Predicted band size: 16 kDa

Observed band size: 30 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Duck Lysozyme C-1.

P00705

Specificity

Predicted to react with Anas platyrhynchos.

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Recombinant full length protein - Duck": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/5000", "WB-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purity >95%.
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Lysozyme C-1 also known as LYZ is an enzyme that plays a strong role in bacteriolysis by hydrolyzing the 14-beta-linkages between the N-acetylmuramic acid and N-acetyl-D-glucosamine residues of peptidoglycan in bacterial cell walls. This protein has a mass of approximately 14.7 kDa and is prominently expressed in a variety of tissues including secretions such as saliva tears and human milk as well as certain immune cells like macrophages and neutrophils.
Biological function summary

This protein acts in innate immunity by destroying bacterial cell walls helping protect against bacterial infections. It operates as a single polypeptide chain and does not require a complex to execute its function. Lysozyme C-1 contributes to the body's first line of defense by targeting and degrading peptidoglycans in the bacteria which can lead to bacterial cell lysis and a reduction in infection.

Pathways

This enzyme has a pivotal role in the immune response pathway specifically influencing the antibacterial pathways within the innate immune system. Lysozyme C-1 works in conjunction with other immune proteins such as lactoferrin and defensins to enhance antibacterial activity. Together they create a hostile environment for bacteria limiting their growth and survival which is critical in maintaining a balanced microbiota.

Lysozyme C-1 connects to conditions like chronic obstructive pulmonary disease (COPD) and inflammatory bowel disease (IBD). Its altered expression or activity can disrupt normal bacterial flora or inadequate immune responses contributing to the pathology of these diseases. The protein defensin which also acts in antimicrobial defense often shows altered expression patterns in cases of such disorders indicating a relationship with lysozyme C-1 in disease progression and defense impairment.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
See full target information Lysozyme C-1
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of biochemical and molecular toxicology 38:e23577 PubMed37934488

2023

Silencing of GDF11 suppresses hepatocyte apoptosis to relieve LPS/D-GalN acute liver failure.

Applications

Unspecified application

Species

Unspecified reactive species

Rongsheng Zhou,Shuang Li,Qun Wang,Yang Bi,Xiaogang Li,Qiang Wang
View all publications
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB108508

Anti-Lysozyme antibody [EPR2994(2)]

RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Lysozyme antibody [EPR2994(2)] (AB108508)

  • 5
  • 4
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Assay Kits

AB102524

Lipase Assay Kit (Colorimetric)

Functional Studies - Lipase Assay Kit (Colorimetric) (AB102524)

  • 0
  • 0
Assay Kits

AB189817

Cellulase Activity Assay kit (Fluorometric)

Functional Studies - Cellulase Activity Assay kit (Fluorometric) (AB189817)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com