AB138707

Anti-Major latex allergen Hev b 5 antibody [5-11.6]

Name: Anti-Major latex allergen Hev b 5 antibody [5-11.6] (ab138707) | Abcam
Brand: Abcam Limited
SKU: AB138707

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(1 Publication)

Mouse Monoclonal Major latex allergen Hev b 5 antibody. Suitable for ELISA and reacts with Hevea brasiliensis samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Hevea brasiliensis ALL5_HEVBR.

View Alternative Names

Major latex allergen Hev b 5

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

5-11.6

Isotype

IgG2b

Carrier free

Reacts with

Hevea brasiliensis

Applications

ELISA

applications

Immunogen

Recombinant Full Length Protein corresponding to Hevea brasiliensis ALL5_HEVBR. The exact immunogen used to generate this antibody is proprietary information.

Q39967

Specificity

ab138707 reacts with both recombinant and native Major latex allergen Hev b 5.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Hevea brasiliensis": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Major latex allergen Hev b 5 also known as the acidic protein 5 is a 16 kDa protein found in the latex of Hevea brasiliensis the rubber tree. This protein functions mechanistically by acting as a prohevein which serves structural and binding roles essential for latex production. Hev b 5 exists mainly within the cytosolic compartments of rubber tree laticifers the specialized cells responsible for the synthesis and storage of latex. Its presence is integral to the mechanical stability and processing of latex particles.

Biological function summary

The major latex allergen Hev b 5 contributes to the natural defense mechanism of the rubber tree against pathogens. While not precisely part of a large multiprotein complex its structural characteristics facilitate aggregation tendencies with other latex proteins strengthening the physical properties of natural rubber. This aggregation also serves connections with other allergenic proteins increasing their surface availability potentially enhancing allergenicity in susceptible individuals.

Pathways

Proteins derived from Hev b 5 participate in pathways related to the plant's intrinsic immune defense. One key pathway involves its role in latex coagulation where it interacts with hevein-like proteins enhancing the tree's response to mechanical injury. Additionally Hev b 5 links to the biosynthesis and modification pathway of natural rubber sharing proteomic networks with proteins like Hev b 1 and Hev b 3 which mediate the cross-linking process essential for latex formation.

Major latex allergen Hev b 5 plays a significant role in latex allergy a prevalent concern for individuals with occupational exposure. This allergen similar to related proteins like Hev b 1 and Hev b 6 triggers IgE-mediated allergic responses leading to disorders such as contact dermatitis and respiratory complications. Additionally Hev b 5's structural similarities to other plant-derived allergens can invoke cross-reactivity heightening allergic conditions in sensitized patients.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

See full target information ALL5_HEVBR

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Parasites & vectors 18:333 PubMed40760662

2025

Toxoplasma gondii-induced host's high secretion of 25-hydroxycholesterol for immunoprotection.

Applications

Unspecified application

Species

Unspecified reactive species

Zi-Han Yang,Wei-Ling Wu,Jia-Jia Zheng,Chi Zhang,Ying-Ying Lu,Hong-Juan Peng

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Major latex allergen Hev b 5 antibody [5-11.6]

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (1)

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