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AB155786

Anti-MAML1 antibody - N-terminal

3

(5 Reviews)

|

(4 Publications)

Rabbit Polyclonal MAML1 antibody. Suitable for WB, ICC/IF and reacts with Mouse, Human samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human MAML1 aa 1-50.

View Alternative Names

KIAA0200, MAML1, Mastermind-like protein 1, Mam-1

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-MAML1 antibody - N-terminal (AB155786)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-MAML1 antibody - N-terminal (AB155786)

Confocal immunofluorescence analysis of paraformaldehyde-fixed HeLa cells, labeling MAML1 with ab155786 at 1/500 dilution. Alpha-tubulin filaments are labeled in red.

Western blot - Anti-MAML1 antibody - N-terminal (AB155786)
  • WB

Unknown

Western blot - Anti-MAML1 antibody - N-terminal (AB155786)

7.5% SDS PAGE

All lanes:

Western blot - Anti-MAML1 antibody - N-terminal (ab155786) at 1/1000 dilution

Lane 1:

HeLa whole cell lysate at 30 µg

Lane 2:

HeLa nuclear cell lysate at 30 µg

Predicted band size: 108 kDa

false

Western blot - Anti-MAML1 antibody - N-terminal (AB155786)
  • WB

Unknown

Western blot - Anti-MAML1 antibody - N-terminal (AB155786)

7.5% SDS PAGE

All lanes:

Western blot - Anti-MAML1 antibody - N-terminal (ab155786) at 1/1000 dilution

All lanes:

Mouse heart whole cell lysate at 50 µg

Predicted band size: 108 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

ICC/IF, WB

applications

Immunogen

Synthetic Peptide within Human MAML1 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

Q92585

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/1000", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 10% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.
See full target information MAML1
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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

PLoS genetics 18:e1010335 PubMed35951645

2022

A Drosophila Su(H) model of Adams-Oliver Syndrome reveals cofactor titration as a mechanism underlying developmental defects.

Applications

Unspecified application

Species

Unspecified reactive species

Ellen K Gagliani,Lisa M Gutzwiller,Yi Kuang,Yoshinobu Odaka,Phillipp Hoffmeister,Stefanie Hauff,Aleksandra Turkiewicz,Emily Harding-Theobald,Patrick J Dolph,Tilman Borggrefe,Franz Oswald,Brian Gebelein,Rhett A Kovall

Bioengineered 13:2194-2206 PubMed35030977

2022

Enabled homolog (ENAH) regulated by RNA binding protein splicing factor 3b subunit 4 (SF3B4) exacerbates the proliferation, invasion and migration of hepatocellular carcinoma cells via Notch signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Guoming Deng,Yufeng Luo,Yaoming Zhang,Jinfeng Zhang,Zongyun He

Nucleic acids research 48:3496-3512 PubMed32107550

2020

HDAC3 functions as a positive regulator in Notch signal transduction.

Applications

Unspecified application

Species

Unspecified reactive species

Francesca Ferrante,Benedetto Daniele Giaimo,Marek Bartkuhn,Tobias Zimmermann,Viola Close,Daniel Mertens,Andrea Nist,Thorsten Stiewe,Johanna Meier-Soelch,Michael Kracht,Steffen Just,Patricia Klöble,Franz Oswald,Tilman Borggrefe

Molecular therapy. Nucleic acids 16:745-757 PubMed31146256

2019

miR-133b Downregulation Reduces Vulnerable Plaque Formation in Mice with AS through Inhibiting Macrophage Immune Responses.

Applications

Unspecified application

Species

Unspecified reactive species

Cheng-Gen Zheng,Bing-Yu Chen,Ren-Hua Sun,Xiao-Zhou Mou,Fang Han,Qian Li,Hai-Jun Huang,Jing-Quan Liu,Yue-Xing Tu
View all publications
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Product promise

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