Anti-Mammaglobin A antibody [MGB1/2000]
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(1 Publication)
Mouse Monoclonal Mammaglobin A antibody. Suitable for IHC-P, WB, Protein Array and reacts with Human, Recombinant full length protein - Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human SCGB2A2.
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MGB1, UGB2, SCGB2A2, Mammaglobin-A, Mammaglobin-1, Secretoglobin family 2A member 2
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mammaglobin A antibody [MGB1/2000] (AB238018)
Formalin-fixed, paraffin-embedded human breast carcinoma tissue stained for Mammaglocin A using ab238018 at 0.2 μg/ml in immunohistochemical analysis.
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mammaglobin A antibody [MGB1/2000] (AB238018)
Formalin-fixed, paraffin-embedded human breast carcinoma tissue stained for Mammaglocin A using ab238018 at 0.2 μg/ml in immunohistochemical analysis.
- WB
Supplier Data
Western blot - Anti-Mammaglobin A antibody [MGB1/2000] (AB238018)
All lanes:
Western blot - Anti-Mammaglobin A antibody [MGB1/2000] (ab238018) at 2 µg/mL
Lane 1:
HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
Lane 2:
MCF7 (human breast adenocarcinoma cell line) whole cell lysate
Lane 3:
SK-BR-3 (human mammary gland adenocarcinoma cell line) whole cell lysate
Lane 4:
T-47D (Human ductal breast epithelial tumor cell line) whole cell lysate
Predicted band size: 10 kDa
false
- Protein Array
Unknown
Protein Array - Anti-Mammaglobin A antibody [MGB1/2000] (AB238018)
ab238018 was tested in protein array against over 19000 different full-length human proteins.
Z- and S- Score : The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.
A MAb is specific to its intended target if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Reactivity data
Properties and storage information
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Shipped at conditions
Appropriate short-term storage duration
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Appropriate long-term storage conditions
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Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Mammaglobin A functions as a glycoprotein. Its precise biological role remains unclear but scientists propose it plays a role in secretory processes due to its presence in epithelial cells of the mammary glands. This protein itself is not known to participate in a larger complex. The significance of Mammaglobin A as a marker rather than an active enzyme or receptor suggests its potential involvement in processes specific to breast tissue.
Pathways
Mammaglobin A interacts within pathways involving sex steroid hormone signaling reflecting its expression in mammary tissue. This protein's expression is possibly regulated by hormonal pathways like the estrogen pathway which plays a significant role in breast tissue development and differentiation. It does not actively participate with related proteins but might be an indicator of pathway activities associated with specific tissues or conditions.
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Target data
Publications (1)
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The Journal of investigative dermatology 143:2052-2064.e5 PubMed37044260
2023
Applications
Unspecified application
Species
Unspecified reactive species
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