Anti-CD206 antibody [15-2]
4
(11 Reviews)
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(97 Publications)
Mouse Monoclonal Mannose Receptor antibody. Suitable for IHC-Fr and reacts with Human samples. Cited in 97 publications. Immunogen corresponding to Native Full Length Protein corresponding to Human MRC1.
View Alternative Names
CD206, CLEC13D, CLEC13DL, MRC1L1, MRC1, Macrophage mannose receptor 1, MMR, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, Human mannose receptor, Macrophage mannose receptor 1-like protein 1, hMR
- IHC-Fr
AbReview14982****
Immunohistochemistry (Frozen sections) - Anti-CD206 antibody [15-2] (AB8918)
ab8918 staining CD206 in human mammary gland tissue section by Immunohistochemistry (Frozen sections). Tissue samples were fixed with 70% Ethanol and blocking for 10 minutes at RT was performed. The sample was incubated with primary antibody (1/10) for 1 hour. A HRP-conjugated mouse polyclonal to mouse IgG was used undiluted as secondary antibody.
This image is a courtesy of Pat Bell
- IHC-Fr
Supplier Data
Immunohistochemistry (Frozen sections) - Anti-CD206 antibody [15-2] (AB8918)
Frozen sections of human tonsil. ab8918 was used in a dilution of 1/25 and shows staining of endothelia of lymph vessels.
- IHC-Fr
AbReview44958****
Immunohistochemistry (Frozen sections) - Anti-CD206 antibody [15-2] (AB8918)
ab8918 staining CD206 in human endometriosis tissue sections by Immunohistochemistry (IHC-Fr - frozen sections). Tissue was fixed with acetone and blocked with 10% serum for 1 hour at 22°C. Samples were incubated with primary antibody (1/10 in PBS + 1% NGS) for 16 hours at 4°C. An undiluted HRP-conjugated goat anti-mouse IgG polyclonal was used as the secondary antibody.
This image is courtesy of an Abreview submitted by Aimée-Lys Rusesabagina
- IHC-Fr
AbReview31720****
Immunohistochemistry (Frozen sections) - Anti-CD206 antibody [15-2] (AB8918)
Immunohistochemical analysis of murine uterus tissue sections, staining CD206 with ab8918.
Tissue was fixed with paraformaldehyde and blocked with 3% BSA for 30 minutes at room temperature. Samples were incubated with primary antibody (1/40 in 1% BSA) for 1.5 hours. An undiluted HRP-conjugated rabbit anti-mouse polyclonal IgG was used as the secondary antibody.
This image is courtesy of an anonymous Abreview
Related conjugates and formulations (5)
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660 APC
APC Anti-CD206 antibody [15-2]
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519 FITC
FITC Anti-CD206 antibody [15-2]
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578 PE
PE Anti-CD206 antibody [15-2]
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778 PE/Cy7®
PE/Cy7® Anti-CD206 antibody [15-2]
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695 PerCP/Cy5.5®
PerCP/Cy5.5® Anti-CD206 antibody [15-2]
Reactivity data
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Supplementary information
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Biological function summary
The Mannose Receptor functions in pathogen recognition and clearance by binding to specific carbohydrates on the pathogen's surface. It is not part of a larger molecular complex but works independently to facilitate phagocytosis. The receptor is essential in immune responses allowing macrophages and dendritic cells to efficiently capture and process antigens for presentation to T cells. This enables the initiation of adaptive immune responses.
Pathways
Researchers know that the Mannose Receptor plays an important role in immune signaling pathways particularly in antigen processing and presentation. It interacts with proteins involved in these pathways including those necessary for the internalization and degradation of bound antigens. Moreover it works alongside scavenger receptors contributing to the regulation of immune and inflammatory responses.
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Publications (97)
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Acta biochimica et biophysica Sinica : PubMed40734554
2025
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The Journal of clinical investigation 135: PubMed40471675
2025
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PloS one 20:e0323222 PubMed40338892
2025
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Frontiers in bioengineering and biotechnology 13:1524013 PubMed40078791
2025
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Journal of functional biomaterials 16: PubMed39997590
2025
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PloS one 20:e0318107 PubMed39932994
2025
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The FEBS journal 291:5214-5235 PubMed39434428
2024
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Respiratory research 25:351 PubMed39342180
2024
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Materials today. Bio 28:101250 PubMed39318371
2024
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World journal of diabetes 15:1589-1602 PubMed39099815
2024
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