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AB115511

Anti-MAP1 antibody

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(1 Publication)

Rabbit Polyclonal MAP1 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human MOAP1 conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

PNMA4, MOAP1, Modulator of apoptosis 1, MAP-1, MAP1, Paraneoplastic antigen Ma4

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAP1 antibody (AB115511)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAP1 antibody (AB115511)

ab115511 at 2.5ug/ml staining MAP1 in Human brain (cortex) tissue by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human MOAP1 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q96BY2

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "2.5 µg/mL", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-80°C
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Retrotransposon-derived protein that forms virion-like capsids (By similarity). Acts as an effector of BAX during apoptosis : enriched at outer mitochondria membrane and associates with BAX upon induction of apoptosis, facilitating BAX-dependent mitochondrial outer membrane permeabilization and apoptosis (PubMed : 11060313, PubMed : 16199525). Required for death receptor-dependent apoptosis (PubMed : 11060313). When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation (PubMed : 15949439). Also promotes autophagy : promotes phagophore closure via association with ATG8 proteins (PubMed : 33783314). Acts as an inhibitor of the NFE2L2/NRF2 pathway via interaction with SQSTM1 : interaction promotes dissociation of SQSTM1 inclusion bodies that sequester KEAP1, relieving inactivation of the BCR(KEAP1) complex (PubMed : 33393215).
See full target information MOAP1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Biology 10: PubMed34439938

2021

Vitamin D Is Necessary for Murine Gastric Epithelial Homeostasis.

Applications

Unspecified application

Species

Unspecified reactive species

Ifrah Ismail Ali,Iltaf Shah,Sayed Marzouk,Sherif M Karam,Asma Al Menhali
View all publications
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Product promise

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