AB92434

Anti-MAP2 antibody - Neuronal Marker

Name: Anti-MAP2 antibody - Neuronal Marker (ab92434) | Abcam
Brand: Abcam Limited
SKU: AB92434
Price: 400 USD
Availability: InStock
Rating: 5 (2 reviews)

Lab Essentials
What is this?

(2 Reviews)

(105 Publications)

Anti-MAP2 antibody (ab92434) is a chicken polyclonal antibody detecting MAP2 in Western Blot. Suitable for Human, Rat.

- Over 60 publications
- Trusted since 2010

View Alternative Names

Microtubule-associated protein 2, MAP-2, MAP2

3 Images

Supplier Data

Immunocytochemistry - Anti-MAP2 antibody - Neuronal Marker (AB92434)

ab92434 at 1/2500 dilution staining MAP2 in mixed neuron/glial cultures by Immunofluorescence. The perikarya and dendrites of neurons are strongly and specifically stained with the MAP2 antibody (red). Cell nuclei are visualized with DAPI DNA stain.

AbReview41831****

Immunocytochemistry - Anti-MAP2 antibody - Neuronal Marker (AB92434)

ab92434 staining MAP2 in mouse brain neurons by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with paraformaldehyde and blocked with 5% serum for 1 hour at 20°C. Samples were incubated with primary antibody (1/2500 in PBS) for 24 hours at 4°C. ab150169, a goat anti-chicken Alexa Fluor® 488 (1/500) was used as the secondary antibody.

This image is courtesy of an Abreview submitted by Kirsty Ireland

Unknown

Western blot - Anti-MAP2 antibody - Neuronal Marker (AB92434)

All lanes:

Western blot - Anti-MAP2 antibody - Neuronal Marker (ab92434) at 1/20000 dilution

All lanes:

Rat cerebral cortex lysate

Predicted band size: 199 kDa

false

Key facts

Host species

Chicken

Clonality

Polyclonal

Isotype

IgY

Carrier free

Reacts with

Rat, Human

Applications

WB, ICC

applications

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICC-species-checked": "testedAndGuaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "ICC-species-checked": "guaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/20000", "WB-species-notes": "<p></p>" } } }

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Product details

What is this antibody validated in?
Anti-MAP2 antibody (ab92434) is a chicken polyclonal antibody and is validated for use in Western Blot (WB) in Human, Rat samples.

What is the molecular weight of MAP2?
Anti-MAP2 (ab92434) specifically detects a band for MAP2 (UniProt: P11137) at a molecular weight of 280kDa.

Trusted by the scientific community
Anti-MAP2 (ab92434) was first used in a scientific publication in 2010 and has been cited over 60 times in peer-reviewed journals.

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Properties and storage information

Form

Liquid

Purity

IgY fraction

Storage buffer

Preservative: 0.065% Sodium azide

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

See full target information MAP2

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Publications (105)

Recent publications for all applications. Explore the full list and refine your search

iScience 28:113541 PubMed41050933

2025

Reproducibility of PD patient-specific midbrain organoid data for disease modeling.

Applications

Unspecified application

Species

Unspecified reactive species

Elisa Zuccoli,Haya Al Sawaf,Mona Tuzza,Sarah L Nickels,Alise Zagare,Jens C Schwamborn

Nature communications 16:8747 PubMed41034202

2025

Cassini: streamlined and scalable method for in situ profiling of RNA and protein.

Applications

Unspecified application

Species

Unspecified reactive species

Nicolas Lapique,Michael Taewoo Kim,Nicholas Thom,Naeem M Nadaf,Juan Pineda,Evan Z Macosko

iScience 28:113246 PubMed40894882

2025

Addressing neuroinflammation in human induced pluripotent stem cell-derived central nervous system neurospheroids.

Applications

Unspecified application

Species

Unspecified reactive species

Catarina M Gomes,Daniel Simão,Carolina Cardoso Gonçalves,Gabriela Silva,Beatriz Painho,Paula Marques Alves,Catarina Brito

PloS one 20:e0329268 PubMed40802598

2025

Anti-obesity compounds, Semaglutide and LiPR, and PrRP do not change the proportion of human and mouse POMC+ neurons.

Applications

Unspecified application

Species

Unspecified reactive species

Sara K M Jörgensen,May Surridge-Smith,Kimberley Jones,Lenka Maletínská,Nicholas D Allen,David Petrik

Communications biology 8:1139 PubMed40745206

2025

Stoichiometric 14-3-3ζ binding promotes phospho-Tau microtubule dissociation and reduces aggregation and condensation.

Applications

Unspecified application

Species

Unspecified reactive species

Janine Hochmair,Maxime C M van den Oetelaar,Leandre Ravatt,Lisa Diez,Lenne J M Lemmens,Renata Ponce-Lina,Rithika Sankar,Maximilian Franck,Gesa Nolte,Ekaterina Semenova,Satabdee Mohapatra,Christian Ottmann,Luc Brunsveld,Susanne Wegmann

STAR protocols 6:103965 PubMed40705596

2025

Protocol to generate species-specific astrocyte-conditioned medium for human organoid neuron maturation.

Applications

Unspecified application

Species

Unspecified reactive species

Honghui Zheng,Wenxin Xu,Feifei Yu,Jiani Xu,Mingyue Jiang,Ning Ma,Zhicheng Shao,Shaohua Ma

Nature structural & molecular biology 32:1932-1946 PubMed40646310

2025

Comparative CRISPRi screens reveal a human stem cell dependence on mRNA translation-coupled quality control.

Applications

Unspecified application

Species

Unspecified reactive species

Geraldine Rodschinka,Sergio Forcelloni,Felix M Kühner,Sascha Wani,Henrick Riemenschneider,Dieter Edbauer,Andrew Behrens,Danny D Nedialkova

Science advances 11:eads5006 PubMed40614201

2025

SARS-CoV-2 induces Alzheimer's disease-related amyloid-β pathology in ex vivo human retinal explants and retinal organoids.

Applications

Unspecified application

Species

Unspecified reactive species

Sean J Miller,Rahul M Dhodapkar,Hande Eda Sutova,Yao Xue,Seunghoon Lee,Robert Logan,Chongzhao Ran,Sagar Bhatta,Ashley Gomm,In Gyoung Ju,Michael Heyang,Rayyan Y Darji,Marcello DiStasio,Rudolph E Tanzi,Can Zhang,Z Jimmy Zhou,Brian P Hafler

The Journal of neuroscience : the official journal of the Society for Neuroscience 45: PubMed40335156

2025

CXCL12 Engages Cortical Inhibitory Neurons to Enhance Dendritic Spine Plasticity and Structured Network Activity.

Applications

Unspecified application

Species

Unspecified reactive species

Chunta Ho,Jared Luchetta,Bradley Nash,Lindsay K Festa,James A Johnson,Ahmet Sacan,Joshua G Jackson,Antonio Sanz-Clemente,Renato Brandimarti,Olimpia Meucci

Nature communications 16:2845 PubMed40122897

2025

Astrocyte-secreted cues promote neural maturation and augment activity in human forebrain organoids.

Applications

Unspecified application

Species

Unspecified reactive species

Honghui Zheng,Yilin Feng,Jiyuan Tang,Feifei Yu,Zitian Wang,Jiani Xu,Cheng Hai,Mingyue Jiang,Yifan Cheng,Zhicheng Shao,Ning Ma,Peter E Lobie,Shaohua Ma

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-MAP2 antibody - Neuronal Marker

Immunocytochemistry - Anti-MAP2 antibody - Neuronal Marker (AB92434)

Immunocytochemistry - Anti-MAP2 antibody - Neuronal Marker (AB92434)

Western blot - Anti-MAP2 antibody - Neuronal Marker (AB92434)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

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Reactivity data

Product details

Properties and storage information

Form

Purity

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (105)

Product promise