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AB198692

Anti-MARC1 antibody

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(2 Publications)

Rabbit Polyclonal MARC1 antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human MTARC1.

View Alternative Names

MARC1, MOSC1, MTARC1, Mitochondrial amidoxime-reducing component 1, mARC1, Molybdenum cofactor sulfurase C-terminal domain-containing protein 1, MOSC domain-containing protein 1, Moco sulfurase C-terminal domain-containing protein 1

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARC1 antibody (AB198692)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARC1 antibody (AB198692)

Immunohistochemical analysis of paraffin embedded human gastric cancer tissue labeling MARC1 with ab198692 at a 1/40 dilution.

Western blot - Anti-MARC1 antibody (AB198692)
  • WB

Supplier Data

Western blot - Anti-MARC1 antibody (AB198692)

Gel : 10%SDS-PAGE

All lanes:

Western blot - Anti-MARC1 antibody (ab198692) at 1/1400 dilution

All lanes:

HepG2 cell lysate at 40 µg

Predicted band size: 37 kDa

true

Exposure time: 40s

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Synthetic Peptide within Human MTARC1. The exact immunogen used to generate this antibody is proprietary information.

Q5VT66

Specificity

ab198692 detects endogenous levels of total MARC1 Antibody.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles (PubMed : 19053771, PubMed : 21029045, PubMed : 30397129). As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability (PubMed : 19053771). May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis (PubMed : 21029045). Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction (PubMed : 19053771, PubMed : 21029045).
See full target information MTARC1
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Cell reports 42:112525 PubMed37243592

2023

Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease.

Applications

Unspecified application

Species

Unspecified reactive species

Theodore S Kapellos,Kevin Baßler,Wataru Fujii,Christina Nalkurthi,Anna C Schaar,Lorenzo Bonaguro,Tal Pecht,Izabela Galvao,Shobhit Agrawal,Adem Saglam,Erica Dudkin,Amit Frishberg,Elena de Domenico,Arik Horne,Chantal Donovan,Richard Y Kim,David Gallego-Ortega,Tessa E Gillett,Meshal Ansari,Jonas Schulte-Schrepping,Nina Offermann,Ignazio Antignano,Burcu Sivri,Wenying Lu,Mathew S Eapen,Martina van Uelft,Collins Osei-Sarpong,Maarten van den Berge,Hylke C Donker,Harry J M Groen,Sukhwinder S Sohal,Johanna Klein,Tina Schreiber,Andreas Feißt,Ali Önder Yildirim,Herbert B Schiller,Martijn C Nawijn,Matthias Becker,Kristian Händler,Marc Beyer,Melania Capasso,Thomas Ulas,Jan Hasenauer,Carmen Pizarro,Fabian J Theis,Philip M Hansbro,Dirk Skowasch,Joachim L Schultze

Nature communications 12:4980 PubMed34404792

2021

Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery.

Applications

Unspecified application

Species

Unspecified reactive species

Wei Qin,Samuel A Myers,Dominique K Carey,Steven A Carr,Alice Y Ting
View all publications
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Product promise

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