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AB229082

Anti-MARC1 antibody

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(1 Publication)

Rabbit Polyclonal MARC1 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human MTARC1.

View Alternative Names

MARC1, MOSC1, MTARC1, Mitochondrial amidoxime-reducing component 1, mARC1, Molybdenum cofactor sulfurase C-terminal domain-containing protein 1, MOSC domain-containing protein 1, Moco sulfurase C-terminal domain-containing protein 1

1 Images
Immunocytochemistry/ Immunofluorescence - Anti-MARC1 antibody (AB229082)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-MARC1 antibody (AB229082)

2% Paraformaldehyde/PBS-fixed HeLa (Human epithelial cell line from cervix adenocarcinoma) cells stained for MARC1 protein (green) using ab229082 at 1/500 dilution in ICC/IF.

Nuclear counterstain : Hoechst 33342 (blue).

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human MTARC1. The exact immunogen used to generate this antibody is proprietary information.

Q5VT66

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/1000", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles (PubMed : 19053771, PubMed : 21029045, PubMed : 30397129). As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability (PubMed : 19053771). May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis (PubMed : 21029045). Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction (PubMed : 19053771, PubMed : 21029045).
See full target information MTARC1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Science advances 11:eadv2453 PubMed40768568

2025

AND-1 is a critical regulator of R-loop dynamics and a target to overcome endocrine resistance.

Applications

Unspecified application

Species

Unspecified reactive species

Zhuqing Li,Yihan Peng,Huai-Chin Chiang,Yanjun Gao,Chen Chu,Yi Zhang,Muhammad Jameel Mughal,Chengyu Liu,Rong Li,Huadong Pei,Wenge Zhu
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Product promise

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