AB233111

Anti-MARC1 antibody

Name: Anti-MARC1 antibody (ab233111) | Abcam
Brand: Abcam Limited
SKU: AB233111
Price: 510 USD
Availability: InStock

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(1 Publication)

Rabbit Polyclonal MARC1 antibody. Suitable for WB, IHC-P and reacts with Human, Cow samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human MTARC1 aa 1 to C-terminus.

View Alternative Names

MARC1, MOSC1, MTARC1, Mitochondrial amidoxime-reducing component 1, mARC1, Molybdenum cofactor sulfurase C-terminal domain-containing protein 1, MOSC domain-containing protein 1, Moco sulfurase C-terminal domain-containing protein 1

9 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARC1 antibody (AB233111)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARC1 antibody (AB233111)

Paraffin-embedded human liver tissue stained for MARC1 using ab233111 at 20 μg/ml in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARC1 antibody (AB233111)

Paraffin-embedded human stomach tissue stained for MARC1 using ab233111 at 20 μg/ml in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARC1 antibody (AB233111)

Paraffin-embedded human kidney tissue stained for MARC1 using ab233111 at 20 μg/ml in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARC1 antibody (AB233111)

Paraffin-embedded human stomach cancer tissue stained for MARC1 using ab233111 at 20 μg/ml in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARC1 antibody (AB233111)

Paraffin-embedded human glioma tissue stained for MARC1 using ab233111 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Supplier Data

Western blot - Anti-MARC1 antibody (AB233111)

All lanes:

Western blot - Anti-MARC1 antibody (ab233111) at 2 µg/mL

All lanes:

Cow liver lysate

Secondary

All lanes:

HRP-Linked Guinea pig Anti-Rabbit Ab at 1/1000 dilution

Predicted band size: 37 kDa

false

Supplier Data

Western blot - Anti-MARC1 antibody (AB233111)

All lanes:

Western blot - Anti-MARC1 antibody (ab233111) at 2 µg/mL

All lanes:

Human lung lysate

Secondary

All lanes:

HRP-Linked Guinea pig Anti-Rabbit Ab

Predicted band size: 37 kDa

false

Supplier Data

Western blot - Anti-MARC1 antibody (AB233111)

All lanes:

Western blot - Anti-MARC1 antibody (ab233111) at 2 µg/mL

All lanes:

HepG2 (human liver hepatocellular carcinoma cell line) cell lysate

Secondary

All lanes:

HRP-Linked Guinea pig Anti-Rabbit Ab

Predicted band size: 37 kDa

false

Supplier Data

Western blot - Anti-MARC1 antibody (AB233111)

All lanes:

Western blot - Anti-MARC1 antibody (ab233111) at 2 µg/mL

All lanes:

Recombinant human MARC1 protein

Predicted band size: 37 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Cow, Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human MTARC1 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q5VT66

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "" }, "Cow": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

ab233111 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.

Storage buffer

pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles (PubMed : 19053771, PubMed : 21029045, PubMed : 30397129). As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability (PubMed : 19053771). May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis (PubMed : 21029045). Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction (PubMed : 19053771, PubMed : 21029045).

See full target information MTARC1

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of cell biology 221: PubMed35670764

2022

Fbxo7 promotes Cdk6 activity to inhibit PFKP and glycolysis in T cells.

Applications

Unspecified application

Species

Unspecified reactive species

Rebecca Harris,Ming Yang,Christina Schmidt,Chloe Royet,Sarbjit Singh,Amarnath Natarajan,May Morris,Christian Frezza,Heike Laman

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-MARC1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARC1 antibody (AB233111)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARC1 antibody (AB233111)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARC1 antibody (AB233111)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARC1 antibody (AB233111)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARC1 antibody (AB233111)

Western blot - Anti-MARC1 antibody (AB233111)

Western blot - Anti-MARC1 antibody (AB233111)

Western blot - Anti-MARC1 antibody (AB233111)

Western blot - Anti-MARC1 antibody (AB233111)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (1)

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