AB231046

Anti-MARCO antibody

Name: Anti-MARCO antibody (ab231046) | Abcam
Brand: Abcam Limited
SKU: AB231046
Rating: 5 (1 reviews)

(1 Review)

(9 Publications)

Rabbit Polyclonal MARCO antibody. Suitable for WB, IHC-P and reacts with Rat samples. Cited in 9 publications.

View Alternative Names

SCARA2, MARCO, Macrophage receptor MARCO, Macrophage receptor with collagenous structure, Scavenger receptor class A member 2

4 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARCO antibody (AB231046)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARCO antibody (AB231046)

Formalin-fixed, paraffin-embedded rat lung tissue stained for MARCO with ab231046 at 20 μg/ml in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARCO antibody (AB231046)

Paraffin-embedded rat thymus tissue stained for MARCO with ab231046 at 20 μg/ml in immunohistochemical analysis. AEC staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MARCO antibody (AB231046)

DAB staining on IHC-P : Immunohistochemical analysis of paraffin-embedded Rat Liver Tissue labelling MARCO with ab231046 at 20µg/ml, followed by HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody at 2µg/mL. Secondary antibody only control : Used PBS instead of primary antibody, secondary antibody is 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

Supplier Data

Western blot - Anti-MARCO antibody (AB231046)

All lanes:

Western blot - Anti-MARCO antibody (ab231046) at 1 µg/mL

All lanes:

Rat thymus gland lysate

Secondary

All lanes:

HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody at 0.2 µg/mL

Predicted band size: 52 kDa

Observed band size: 52 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Rat

Applications

WB, IHC-P

applications

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "The rat recommendation is based on the IHC-P results. We do not guarantee WB for rat.", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

ab231046 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.

Storage buffer

pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Pattern recognition receptor (PRR) which binds Gram-positive and Gram-negative bacteria (PubMed : 9468508). Also plays a role in binding of unopsonized particles by alveolar macrophages (By similarity). Binds to the secretoglobin SCGB3A2 (PubMed : 12847263).

See full target information MARCO

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Publications (9)

Recent publications for all applications. Explore the full list and refine your search

NPJ Regenerative medicine 9:37 PubMed39639015

2024

Attenuation of skin injury by a MARCO targeting PLGA nanoparticle.

Applications

Unspecified application

Species

Unspecified reactive species

Ummiye V Onay,Dan Xu,Dauren Biyashev,Spencer T Evans,Michael M Demczuk,Tobias Neef,Joseph R Podojil,Sara Beddow,Nathan C Gianneschi,I Caroline Le Poole,Stephen D Miller,Kurt Q Lu

Arteriosclerosis, thrombosis, and vascular biology 44:720-740 PubMed38269588

2024

Diacylglycerols and Lysophosphatidic Acid, Enriched on Lipoprotein(a), Contribute to Monocyte Inflammation.

Applications

Unspecified application

Species

Unspecified reactive species

Kim E Dzobo,Arjen J Cupido,Barend M Mol,Lotte C A Stiekema,Miranda Versloot,Maaike Winkelmeijer,Jorge Peter,Anne-Marije Pennekamp,Stefan R Havik,Frédéric M Vaz,Michel van Weeghel,Koen H M Prange,Johannes H M Levels,Menno P J de Winther,Sotirios Tsimikas,Albert K Groen,Erik S G Stroes,Dominique P V de Kleijn,Jeffrey Kroon

Signal transduction and targeted therapy 7:289 PubMed36008393

2022

The heterogeneous immune landscape between lung adenocarcinoma and squamous carcinoma revealed by single-cell RNA sequencing.

Applications

Unspecified application

Species

Unspecified reactive species

Chengdi Wang,Qiuxiao Yu,Tingting Song,Zhoufeng Wang,Lujia Song,Ying Yang,Jun Shao,Jingwei Li,Yinyun Ni,Ningning Chao,Li Zhang,Weimin Li

Cancer cell 40:424-437.e5 PubMed35303421

2022

Immune phenotypic linkage between colorectal cancer and liver metastasis.

Applications

Unspecified application

Species

Unspecified reactive species

Yedan Liu,Qiming Zhang,Baocai Xing,Nan Luo,Ranran Gao,Kezhuo Yu,Xueda Hu,Zhaode Bu,Jirun Peng,Xianwen Ren,Zemin Zhang

JCI insight 7: PubMed35104243

2022

PLG nanoparticles target fibroblasts and MARCO+ monocytes to reverse multiorgan fibrosis.

Applications

Unspecified application

Species

Unspecified reactive species

Dan Xu,Swati Bhattacharyya,Wenxia Wang,Igal Ifergan,Ming-Yi Alice Chiang Wong,Daniele Procissi,Anjana Yeldandi,Swarna Bale,Roberta Goncalves Marangoni,Craig Horbinski,Stephen D Miller,John Varga

ACS nano 16:2233-2248 PubMed35138811

2022

Lipid Composition of the Cell Membrane Outer Leaflet Regulates Endocytosis of Nanomaterials through Alterations in Scavenger Receptor Activity.

Applications

Unspecified application

Species

Unspecified reactive species

Saeed Nazemidashtarjandi,Vishva M Sharma,Vishwajeet Puri,Amir M Farnoud,Monica M Burdick

Biomedicines 9: PubMed34944635

2021

Comparative Proteomic Analysis of tPVAT during Ang II Infusion.

Applications

Unspecified application

Species

Unspecified reactive species

Xiuying Liang,Haijing Guan,Jingwen Sun,Yan Qi,Wenjuan Yao

BMC infectious diseases 20:590 PubMed32778058

2020

The reduction in CD8PD-1 T cells in liver histological tissue is related to Pegylated IFN-α therapy outcomes in chronic hepatitis B patients.

Applications

Unspecified application

Species

Unspecified reactive species

Ruyu Liu,Yanhui Chen,Jiang Guo,Minghui Li,Yao Lu,Lu Zhang,Ge Shen,Shuling Wu,Min Chang,Leiping Hu,Hongxiao Hao,Henghui Zhang,Yao Xie

Cell 181:442-459.e29 PubMed32302573

2020

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Lei Zhang,Ziyi Li,Katarzyna M Skrzypczynska,Qiao Fang,Wei Zhang,Sarah A O'Brien,Yao He,Lynn Wang,Qiming Zhang,Aeryon Kim,Ranran Gao,Jessica Orf,Tao Wang,Deepali Sawant,Jiajinlong Kang,Dev Bhatt,Daniel Lu,Chi-Ming Li,Aaron S Rapaport,Kristy Perez,Yingjiang Ye,Shan Wang,Xueda Hu,Xianwen Ren,Wenjun Ouyang,Zhanlong Shen,Jackson G Egen,Zemin Zhang,Xin Yu

View all publications

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