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AB200685

Anti-MAS1L antibody

4

(1 Review)

|

(6 Publications)

Rabbit Polyclonal MAS1L antibody. Suitable for WB and reacts with Human, Mouse, Rat samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Human MAS1L aa 1-100.

View Alternative Names

MRG, MAS1L, Mas-related G-protein coupled receptor MRG, MAS-R, MAS1-like

1 Images
Western blot - Anti-MAS1L antibody (AB200685)
  • WB

Supplier Data

Western blot - Anti-MAS1L antibody (AB200685)

All lanes:

Western blot - Anti-MAS1L antibody (ab200685)

Lane 1:

HEK293T whole cell lysate

Lane 2:

NIH3T3 whole cell lysate

Lane 3:

PC12 whole cell lysate

Predicted band size: 42 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Rat, Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human MAS1L aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

P35410

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
Purity is > 95% (by SDS-PAGE).
Storage buffer
pH: 7.2 Preservative: 0.097% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

MAS1L sometimes referred to as MAS1-like is a protein encoded by the MAS1L gene. Its mass is approximately 37 kDa. This protein is expressed in various tissues including the central nervous system and certain peripheral tissues. MAS1L is an integral membrane protein and it localizes on the cell surface which indicates its potential involvement in signaling processes. As a G protein-coupled receptor it plays a role in transmitting signals across the cell membrane.
Biological function summary

MAS1L functions within the context of signal transduction. It engages in biological processes by potentially forming complexes with other proteins or molecules that facilitate signaling activities. This protein's ability to interact with G proteins suggests its involvement in activating downstream cellular responses influencing various cellular functions such as growth differentiation or communication between cells. The MAS1L's role in signaling implicates it in maintaining normal cellular activity and responding to environmental cues.

Pathways

MAS1L engages in signaling cascades potentially linked to the renin-angiotensin system and other related pathways that influence cardiovascular functions. In the renin-angiotensin system similar receptors like the MAS1 receptor participate suggesting that MAS1L could share functional similarities. The renin-angiotensin pathway plays an important role in regulating blood pressure and fluid balance and any interaction involving MAS1L might contribute to these physiological processes.

Abnormal expression or mutation of MAS1L could relate to cardiovascular diseases and neurological disorders. Dysfunctional signaling through MAS1L might contribute to the pathology of hypertension a condition in which the MAS1 receptor also plays a significant role highlighting potential overlap in their functional pathways. Furthermore disruptions in MAS1L activity might affect neurological functions linking it to conditions that compromise nervous system integrity.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information MAS1L
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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Thyroid research 17:22 PubMed39491028

2024

Losartan is more effective than angiotensin (1-7) in preventing thyroxine-induced renal injury in the rat.

Applications

Unspecified application

Species

Unspecified reactive species

Slava Malatiali,Mabayoje Oriowo

Pharmaceutical biology 60:979-989 PubMed35588103

2022

Fraxinol attenuates LPS-induced acute lung injury by equilibrating ACE-Ang II-AT1R and ACE2-Ang (1-7)-Mas and inhibiting NLRP3.

Applications

Unspecified application

Species

Unspecified reactive species

Yan Wu,Xin Yang,Yuanyuan Ju,Fei Zhao

Cells 11: PubMed35563848

2022

Cross-Talk between CB, AT, AT and Mas Receptors Responsible for Blood Pressure Control in the Paraventricular Nucleus of Hypothalamus in Conscious Spontaneously Hypertensive Rats and Their Normotensive Controls.

Applications

Unspecified application

Species

Unspecified reactive species

Krzysztof Mińczuk,Eberhard Schlicker,Barbara Malinowska

JCI insight 7: PubMed34874920

2022

Angiotensin-(1-7)/MasR axis promotes migration of monocytes/macrophages with a regulatory phenotype to perform phagocytosis and efferocytosis.

Applications

Unspecified application

Species

Unspecified reactive species

Isabella Zaidan,Luciana P Tavares,Michelle A Sugimoto,Kátia M Lima,Graziele L Negreiros-Lima,Lívia Cr Teixeira,Thais C Miranda,Bruno Vs Valiate,Allysson Cramer,Juliana Priscila Vago,Gabriel H Campolina-Silva,Jéssica Am Souza,Laís C Grossi,Vanessa Pinho,Maria Jose Campagnole-Santos,Robson As Santos,Mauro M Teixeira,Izabela Galvão,Lirlândia P Sousa

The Journal of international medical research 48:300060520943453 PubMed32790534

2020

Protective effects of irbesartan and benazepril against vaginal vascular remodeling and fibrosis in female spontaneously hypertensive rats.

Applications

Unspecified application

Species

Unspecified reactive species

Ruixin Ma,Yang Zhao,Xiaorong Yu,Ningyin Li,Qiongying Wang,Wei Liang,Xu Zhao,Jing Yu

Molecular medicine reports 16:8485-8492 PubMed28944898

2017

Effects of IQP, VEP and Spirulina platensis hydrolysates on the local kidney renin angiotensin system in spontaneously hypertensive rats.

Applications

Unspecified application

Species

Unspecified reactive species

Jiahui Zheng,Jingyue Wang,Huanglei Pan,Hongli Wu,Difeng Ren,Jun Lu
View all publications
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