AB196772

Anti-Mast Cell Tryptase antibody

Name: Anti-Mast Cell Tryptase antibody (ab196772) | Abcam
Brand: Abcam Limited
SKU: AB196772
Price: 535 USD
Availability: InStock

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(3 Publications)

Rabbit Polyclonal TRYB1 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human TPSAB1.

View Alternative Names

TPS1, TPS2, TPSB1, TPSAB1, Tryptase alpha/beta-1, Tryptase-1, Tryptase I, Tryptase alpha-1

1 Images

Immunocytochemistry/ Immunofluorescence - Anti-Mast Cell Tryptase antibody (AB196772)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-Mast Cell Tryptase antibody (AB196772)

Immunofluorescent analysis of HeLa cells labeling Mast Cell Tryptase with ab196772 at 1/50 dilution. The lower panel shows nuclear staining with DAPI (blue).

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human TPSAB1. The exact immunogen used to generate this antibody is proprietary information.

Q15661

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS, 0.87% Sodium chloride

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed : 18854315).

See full target information TPSAB1

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 14:7349 PubMed37963864

2023

TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase.

Applications

Unspecified application

Species

Unspecified reactive species

Gang Liu,Tatt Jhong Haw,Malcolm R Starkey,Ashleigh M Philp,Stelios Pavlidis,Christina Nalkurthi,Prema M Nair,Henry M Gomez,Irwan Hanish,Alan Cy Hsu,Elinor Hortle,Sophie Pickles,Joselyn Rojas-Quintero,Raul San Jose Estepar,Jacqueline E Marshall,Richard Y Kim,Adam M Collison,Joerg Mattes,Sobia Idrees,Alen Faiz,Nicole G Hansbro,Ryutaro Fukui,Yusuke Murakami,Hong Sheng Cheng,Nguan Soon Tan,Sanjay H Chotirmall,Jay C Horvat,Paul S Foster,Brian Gg Oliver,Francesca Polverino,Antonio Ieni,Francesco Monaco,Gaetano Caramori,Sukhwinder S Sohal,Ken R Bracke,Peter A Wark,Ian M Adcock,Kensuke Miyake,Don D Sin,Philip M Hansbro

Cell biology international 47:1136-1146 PubMed36906806

2023

Bisphenol A disruption promotes mammary tumor microenvironment via phenotypic cell polarization and inflammatory response.

Applications

Unspecified application

Species

Unspecified reactive species

Thalles F R Ruiz,Simone J Colleta,Diego D Dos Santos,Nayara F C Castro,Ágata S Cabral,Marilia F Calmon,Paula Rahal,Cristiane D Gil,Ana Paula Girol,Patricia S L Vilamaior,Ellen C R Leonel,Sebastião R Taboga

Gastroenterology research and practice 2019:1759842 PubMed31737064

2019

Electroacupuncture Regulates Disorders of Gut-Brain Interaction by Decreasing Corticotropin-Releasing Factor in a Rat Model of IBS.

Applications

Unspecified application

Species

Unspecified reactive species

Ying Chen,Yan Zhao,Dan-Ni Luo,Hui Zheng,Ying Li,Si-Yuan Zhou

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Mast Cell Tryptase antibody

Immunocytochemistry/ Immunofluorescence - Anti-Mast Cell Tryptase antibody (AB196772)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (3)

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