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AB56182

Anti-Matriptase 2 antibody - Catalytic domain

5

(1 Review)

|

(3 Publications)

Rabbit Polyclonal Matriptase 2 antibody. Suitable for WB and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human TMPRSS6.

View Alternative Names

UNQ354/PRO618, TMPRSS6, Transmembrane protease serine 6, Matriptase-2

1 Images
Western blot - Anti-Matriptase 2 antibody - Catalytic domain (AB56182)
  • WB

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Western blot - Anti-Matriptase 2 antibody - Catalytic domain (AB56182)

All lanes:

Western blot - Anti-Matriptase 2 antibody - Catalytic domain (ab56182) at 1/1000 dilution

All lanes:

Cell media from human amnion-derived WISH cells

Predicted band size: 90 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human TMPRSS6. The exact immunogen used to generate this antibody is proprietary information.

Q8IU80

Specificity

ab56182 reacts with human Matripase 2 (TMPRSS6), and does not react with the other TMPRSSs. ab56182 recognizes all but the 2 truncated forms of human Matripase 2.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 2.9% Sodium chloride
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Stable for 12 months at -20°C
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Membrane-bound serine protease (PubMed : 18976966, PubMed : 20518742, PubMed : 25156943, PubMed : 25588876). Through the cleavage of cell surface HJV, a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis (PubMed : 18408718, PubMed : 18976966, PubMed : 25156943).
See full target information TMPRSS6
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 22: PubMed33800732

2021

Matriptase-2 and Hemojuvelin in Hepcidin Regulation: In Vivo Immunoblot Studies in Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Jan Krijt,Jana Frýdlová,Iuliia Gurieva,Petr Přikryl,Martin Báječný,Andrea U Steinbicker,Martin Vokurka,Jaroslav Truksa

Blood cells, molecules & diseases 64:1-7 PubMed28282554

2017

Erythropoietin administration increases splenic erythroferrone protein content and liver TMPRSS6 protein content in rats.

Applications

WB

Species

Rat

Iuliia Gurieva,Jana Frýdlová,Zuzana Rychtarčíková,Martin Vokurka,Jaroslav Truksa,Jan Krijt

PloS one 11:e0148540 PubMed26845567

2016

Effect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and Rats.

Applications

WB

Species

Unspecified reactive species

Jana Frýdlová,Petr Přikryl,Jaroslav Truksa,Lucas L Falke,Xin Du,Iuliia Gurieva,Martin Vokurka,Jan Krijt
View all publications
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