AB106292

Anti-Measles nucleoprotein antibody [2F3]

Name: Anti-Measles nucleoprotein antibody [2F3] (ab106292) | Abcam
Brand: Abcam Limited
SKU: AB106292
Price: 525 USD
Availability: InStock

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(6 Publications)

Mouse Monoclonal NCAP antibody. Suitable for ICC, ELISA, WB, ICC/IF and reacts with Measles virus samples. Cited in 6 publications.

View Alternative Names

NP, N, Nucleoprotein, Nucleocapsid protein, Protein N, NP, N, Nucleoprotein, Nucleocapsid protein, Protein N

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

2F3

Isotype

IgG1

Light chain type

kappa

Carrier free

Reacts with

Measles virus

Applications

ELISA, ICC, ICC/IF, WB

applications

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Measles virus": { "ICC-species-checked": "guaranteed", "ICC-species-dilution-info": "1/100 - 1/500", "ICC-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "1/2000 - 1/10000", "ELISA-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/200 - 1/1000", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

Constituents: 2% Sucrose, 1.21% Tris, 0.75% Glycine

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Forms the helical nucleocapsid (NC) in a ratio of 1 N per 6 ribonucleotides, protecting the genome from nucleases (By similarity). The nucleocapsid (NC) has a helical structure with either 12.35 or 11.64 N per turn, approximately 20 nm in diameter, with a hollow central cavity approximately 5 nm in diameter (By similarity). The encapsidated genomic RNA serves as template for transcription and replication; encapsidation by N is coupled to RNA synthesis (By similarity). Forms the encapsidation complex with the phosphoprotein protein P. Before encapsidation, the newly synthesized free N protein, so-called N0, is chaperoned by P (PubMed : 12573586). Participates, together with P, in the formation of viral factories (viroplasms), which are large inclusions in the host cytoplasm where replication takes place (PubMed : 32270045). N is released in the blood following lysis of measles infected cells, it interacts then with human FCGR2B on immune cells, inducing apoptosis and blocking inflammatory immune response (By similarity).

See full target information N

Additional targets

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Hereditas 161:36 PubMed39342391

2024

A novel approach for breast cancer treatment: the multifaceted antitumor effects of rMeV-Hu191.

Applications

Unspecified application

Species

Unspecified reactive species

Xiao-Yu Zheng,Yao Lv,Ling-Yan Xu,Dong-Ming Zhou,Lan Yu,Zheng-Yan Zhao

Translational oncology 39:101812 PubMed37871517

2023

Synergistic antitumor efficacy of rMV-Hu191 and Olaparib in pancreatic cancer by generating oxidative DNA damage and ROS-dependent apoptosis.

Applications

Unspecified application

Species

Unspecified reactive species

Chu-di Zhang,Li-Hong Jiang,Xue Zhou,Yong-Ping He,Ye Liu,Dong-Ming Zhou,Yao Lv,Ben-Qing Wu,Zheng-Yan Zhao

Cell death discovery 9:171 PubMed37202386

2023

Recombinant measles virus vaccine rMV-Hu191 exerts an oncolytic effect on esophageal squamous cell carcinoma via caspase-3/GSDME-mediated pyroptosis.

Applications

Unspecified application

Species

Unspecified reactive species

Ailing Wu,Zhongyue Li,Yilong Wang,Yi Chen,Jinkai Peng,Mengying Zhu,Yueyue Li,Hai Song,Dongming Zhou,Chudi Zhang,Yao Lv,Zhengyan Zhao

World journal of pediatrics : WJP 15:499-505 PubMed31456156

2019

Establishment of an efficient reverse genetic system of Mumps virus S79 from cloned DNA.

Applications

Unspecified application

Species

Unspecified reactive species

Duo Zhou,Meng-Ying Zhu,Yi-Long Wang,Xiao-Qiang Hao,Dong-Ming Zhou,Rong-Xian Liu,Chu-Di Zhang,Chu-Fan Qu,Zheng-Yan Zhao

Journal of immunological methods 464:1-8 PubMed30056035

2018

Development of a robust and standardized immunoserological assay for detection of anti-measles IgG antibodies in human sera.

Applications

Unspecified application

Species

Unspecified reactive species

Katalin Böröcz,Zsuzsanna Csizmadia,Ákos Markovics,Viktória Mészáros,Kornélia Farkas,Vivien Telek,Vivien Varga,Geofrey Ouma Maloba,Kornélia Bodó,József Najbauer,Tímea Berki,Péter Németh

Virology 518:210-220 PubMed29525671

2018

Enhancement of safety and immunogenicity of the Chinese Hu191 measles virus vaccine by alteration of the S-adenosylmethionine (SAM) binding site in the large polymerase protein.

Applications

Unspecified application

Species

Unspecified reactive species

Yilong Wang,Rongxian Liu,Mijia Lu,Yingzhi Yang,Duo Zhou,Xiaoqiang Hao,Dongming Zhou,Bin Wang,Jianrong Li,Yao-Wei Huang,Zhengyan Zhao

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Measles nucleoprotein antibody [2F3]

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Carrier free

Reacts with

Applications

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Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Product protocols

Target data

Additional targets

Publications (6)

Product promise