AB23974

Anti-Measles nucleoprotein antibody

Name: Anti-Measles nucleoprotein antibody (ab23974) | Abcam
Brand: Abcam Limited
SKU: AB23974
Price: 535 USD
Availability: InStock

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(10 Publications)

Rabbit Polyclonal NCAP antibody. Suitable for ELISA, WB and reacts with Measles virus samples. Cited in 10 publications.

View Alternative Names

NP, N, Nucleoprotein, Nucleocapsid protein, Protein N

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Measles virus

Applications

WB, ELISA

applications

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Measles virus": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purity

Whole antiserum

Storage buffer

Constituents: Whole serum

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Forms the helical nucleocapsid (NC) in a ratio of 1 N per 6 ribonucleotides, protecting the genome from nucleases (By similarity). The nucleocapsid (NC) has a helical structure with either 12.35 or 11.64 N per turn, approximately 20 nm in diameter, with a hollow central cavity approximately 5 nm in diameter (By similarity). The encapsidated genomic RNA serves as template for transcription and replication; encapsidation by N is coupled to RNA synthesis (By similarity). Forms the encapsidation complex with the phosphoprotein protein P (By similarity). Before encapsidation, the newly synthesized free N protein, so-called N0, is chaperoned by P (By similarity). Participates, together with P, in the formation of viral factories (viroplasms), which are large inclusions in the host cytoplasm where replication takes place (By similarity). N is released in the blood following lysis of measles infected cells, it interacts then with human FCGR2B on immune cells, inducing apoptosis and blocking inflammatory immune response (By similarity).

See full target information N

Additional targets

N,N

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Publications (10)

Recent publications for all applications. Explore the full list and refine your search

NPJ vaccines 8:46 PubMed36964176

2023

A protective measles virus-derived vaccine inducing long-lasting immune responses against influenza A virus H7N9.

Applications

Unspecified application

Species

Unspecified reactive species

Cindy Hörner,Anna H Fiedler,Bianca S Bodmer,Lisa Walz,Vivian A Scheuplein,Stefan Hutzler,Mikhail N Matrosovich,Veronika von Messling,Michael D Mühlebach

Developmental neurobiology 80:213-228 PubMed32866337

2020

Type II interferon signaling in the brain during a viral infection with age-dependent pathogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Patrick S Creisher,Manisha N Chandwani,Yashika S Kamte,Jordan R Covvey,Priya Ganesan,Lauren A O'Donnell

Molecular therapy oncolytics 15:186-200 PubMed31788553

2019

High-Affinity DARPin Allows Targeting of MeV to Glioblastoma Multiforme in Combination with Protease Targeting without Loss of Potency.

Applications

Unspecified application

Species

Unspecified reactive species

Jan R H Hanauer,Vivian Koch,Ulrich M Lauer,Michael D Mühlebach

Molecular therapy oncolytics 3:16003 PubMed27119117

2016

Enhanced lysis by bispecific oncolytic measles viruses simultaneously using HER2/neu or EpCAM as target receptors.

Applications

Species

Unspecified reactive species

Jan Rh Hanauer,Lisa Gottschlich,Dennis Riehl,Tillmann Rusch,Vivian Koch,Katrin Friedrich,Stefan Hutzler,Steffen Prüfer,Thorsten Friedel,Kay-Martin Hanschmann,Robert C Münch,Christian Jost,Andreas Plückthun,Klaus Cichutek,Christian J Buchholz,Michael D Mühlebach

PloS one 9:e112014 PubMed25390891

2014

Inhibitors of the interferon response enhance virus replication in vitro.

Applications

Unspecified application

Species

Unspecified reactive species

Claire E Stewart,Richard E Randall,Catherine S Adamson

Gene therapy 20:1033-41 PubMed23719065

2013

An armed oncolytic measles vaccine virus eliminates human hepatoma cells independently of apoptosis.

Applications

Species

Unspecified reactive species

J Lampe,S Bossow,T Weiland,I Smirnow,R Lehmann,W Neubert,M Bitzer,U M Lauer

International journal of oncology 43:103-12 PubMed23612727

2013

Primary resistance phenomena to oncolytic measles vaccine viruses.

Applications

Unspecified application

Species

Unspecified reactive species

Markus Noll,Susanne Berchtold,Johanna Lampe,Nisar P Malek,Michael Bitzer,Ulrich M Lauer

Journal of virology 87:3484-501 PubMed23302892

2013

Innate immune defense defines susceptibility of sarcoma cells to measles vaccine virus-based oncolysis.

Applications

Unspecified application

Species

Unspecified reactive species

Susanne Berchtold,Johanna Lampe,Timo Weiland,Irina Smirnow,Sabine Schleicher,Rupert Handgretinger,Hans-Georg Kopp,Jeanette Reiser,Frank Stubenrauch,Nora Mayer,Nisar P Malek,Michael Bitzer,Ulrich M Lauer

Cancer research 70:7620-9 PubMed20858718

2010

Liver cancer protease activity profiles support therapeutic options with matrix metalloproteinase-activatable oncolytic measles virus.

Applications

Species

Unspecified reactive species

Michael D Mühlebach,Thomas Schaser,Martina Zimmermann,Sorin Armeanu,Kay-Martin O Hanschmann,Roberto Cattaneo,Michael Bitzer,Ulrich M Lauer,Klaus Cichutek,Christian J Buchholz

Journal of virology 82:6190-9 PubMed18417588

2008

A filovirus-unique region of Ebola virus nucleoprotein confers aberrant migration and mediates its incorporation into virions.

Applications

Species

Unspecified reactive species

Wei Shi,Yue Huang,Mark Sutton-Smith,Berangere Tissot,Maria Panico,Howard R Morris,Anne Dell,Stuart M Haslam,Jeffrey Boyington,Barney S Graham,Zhi-Yong Yang,Gary J Nabel

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Measles nucleoprotein antibody

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Reactivity data

Properties and storage information

Form

Purity

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Additional targets

Publications (10)

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