AB327074
Chicken Polyclonal MECP2 antibody. Suitable for WB, IHC and reacts with Mouse, Rat samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human MECP2.
View Alternative Names
Methyl-CpG-binding protein 2, MeCp-2 protein, MeCp2, MECP2
1 Images
- IHC
Supplier Data
Immunohistochemistry - Anti-MeCP2 Antibody (AB327074)
Immunostaining of a section of rat olfactory bulb showing specific labeling of MeCP2 in neuronal nuclei (red) and alpha synuclein (green). The blue is DAPI staining of nuclear DNA.
Reactivity data
{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHC" : {"fullname" : "Immunohistochemistry", "shortname":"IHC"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/20000", "WB-species-notes": "<p></p>", "IHC-species-checked": "guaranteed", "IHC-species-dilution-info": "", "IHC-species-notes": "" }, "Rat": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHC-species-checked": "testedAndGuaranteed", "IHC-species-dilution-info": "1/1000 - 1/2000", "IHC-species-notes": "<p></p>" } } }
Properties and storage information
Form
Liquid
Storage buffer
Preservative: 0.03% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
Product protocols
For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
Product promise
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