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AB327074

Anti-MeCP2 Antibody

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Chicken Polyclonal MECP2 antibody. Suitable for WB, IHC and reacts with Mouse, Rat samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human MECP2.

View Alternative Names

Methyl-CpG-binding protein 2, MeCp-2 protein, MeCp2, MECP2

1 Images
Immunohistochemistry - Anti-MeCP2 Antibody (AB327074)
  • IHC

Supplier Data

Immunohistochemistry - Anti-MeCP2 Antibody (AB327074)

Immunostaining of a section of rat olfactory bulb showing specific labeling of MeCP2 in neuronal nuclei (red) and alpha synuclein (green). The blue is DAPI staining of nuclear DNA.

Key facts

Host species

Chicken

Clonality

Polyclonal

Isotype

IgY

Carrier free

No

Reacts with

Mouse, Rat

Applications

IHC, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human MECP2.

P51608

Specificity

<p>Specific for endogenous levels of the MeCP2 protein. Due to usually high charge, the protein runs at ~75 kDa in SDS-PAGE of mouse brain lysates.</p>

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHC" : {"fullname" : "Immunohistochemistry", "shortname":"IHC"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/20000", "WB-species-notes": "<p></p>", "IHC-species-checked": "guaranteed", "IHC-species-dilution-info": "", "IHC-species-notes": "" }, "Rat": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHC-species-checked": "testedAndGuaranteed", "IHC-species-dilution-info": "1/1000 - 1/2000", "IHC-species-notes": "<p></p>" } } }

Properties and storage information

Form
Liquid
Storage buffer
Preservative: 0.03% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
See full target information MECP2

Product promise

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