AB203038

Anti-Melatonin Receptor 1A/MTNR1A antibody

Name: Anti-Melatonin Receptor 1A/MTNR1A antibody (ab203038) | Abcam
Brand: Abcam Limited
SKU: AB203038
Price: 510 USD
Availability: InStock
Rating: 5 (2 reviews)

(2 Reviews)

(21 Publications)

Rabbit Polyclonal Melatonin Receptor 1A/MTNR1A antibody. Suitable for Flow Cyt and reacts with Human samples. Cited in 21 publications. Immunogen corresponding to Synthetic Peptide within Human Melatonin receptor type 1A aa 200-250 conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

Melatonin receptor type 1A, Mel-1A-R, Mel1a receptor, MTNR1A

1 Images

Flow Cytometry - Anti-Melatonin Receptor 1A/MTNR1A antibody (AB203038)

Flow Cyt

Supplier Data

Flow Cytometry - Anti-Melatonin Receptor 1A/MTNR1A antibody (AB203038)

SH-SY5Y cells were fixed with 4% PFA for 10 min at room temperature, permeabilised with 90% ice-cold methanol for 20 min at -20°C, and incubated in 5% BSA blocking buffer for 30 min at room temperature. Cells were then stained with Melatonin Receptor 1A Antibody (ab203038) at 1/100 dilution in blocking buffer and incubated for 30 min at room temperature, washed twice with 2%BSA in PBS, followed by secondary antibody incubation for 40 min at room temperature. Acquisitions of 20,000 events were performed. Cells stained with primary antibody (green), and isotype control (orange), Goat anti-Rabbit IgG (blue) and blank (black).

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Synthetic Peptide within Human Melatonin receptor type 1A aa 200-250 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

P48039

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/100", "FlowCyt-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

See full target information Melatonin receptor type 1A

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Publications (21)

Recent publications for all applications. Explore the full list and refine your search

Investigative ophthalmology & visual science 66:51 PubMed39976957

2025

Melatonin Alleviates Age-Related Lacrimal Gland Dysfunction Via SIRT-1/NLRP3 Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Chao Wang,Yu-Zhi Li,Huan Guo,Shi-Rui Zhou,Xi Peng,Jia-Song Wang,Hua-Tao Xie,Ming-Chang Zhang

CNS neuroscience & therapeutics 30:e14436 PubMed37736695

2023

Melatonin regulates the circadian rhythm to ameliorate postoperative sleep disorder and neurobehavioral abnormalities in aged mice.

Applications

Unspecified application

Species

Unspecified reactive species

Xixi Jia,Yanan Song,Zhengqian Li,Ning Yang,Taotao Liu,Dengyang Han,Zhuonan Sun,Chengmei Shi,Yang Zhou,Jie Shi,Yajie Liu,Xiangyang Guo

Neurology and therapy 12:2021-2040 PubMed37707705

2023

Effect of PLA2G6 and SMPD1 Variants on the Lipid Metabolism in the Cerebrospinal Fluid of Patients with Parkinson's Disease: A Non-targeted Lipidomics Study.

Applications

Unspecified application

Species

Unspecified reactive species

Yongang Li,GuiKai Ji,Mengjia Lian,Xuan Liu,Ying Xu,Yaxing Gui

Antioxidants (Basel, Switzerland) 12: PubMed36978937

2023

Melatonin Supplementation during the Late Gestational Stage Enhances Reproductive Performance of Sows by Regulating Fluid Shear Stress and Improving Placental Antioxidant Capacity.

Applications

Unspecified application

Species

Unspecified reactive species

Likai Wang,Laiqing Yan,Qi Han,Guangdong Li,Hao Wu,Xiao Ma,Mengmeng Zhao,Wenkui Ma,Pengyun Ji,Ran Zhang,Guoshi Liu

Journal of pineal research 74:e12851 PubMed36639364

2023

Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload.

Applications

Unspecified application

Species

Unspecified reactive species

Xinghua Qin,Yuping Fu,Jiali Fan,Binghua Liu,Peng Liu,Yudi Zhang,Tiannan Jiang,Qiangsun Zheng

American journal of reproductive immunology (New York, N.Y. : 1989) 88:e13585 PubMed35716034

2022

Melatonin regulates proliferation, apoptosis and invasion of trophoblasts in preeclampsia by inhibiting endoplasmic reticulum stress.

Applications

Unspecified application

Species

Unspecified reactive species

Chufan Zhou,Yiling Ding,Ling Yu,Yanting Nie,Mengyuan Yang

Cells 11: PubMed35626727

2022

Activation of MT1/MT2 to Protect Testes and Leydig Cells against Cisplatin-Induced Oxidative Stress through the SIRT1/Nrf2 Signaling Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Junqiang Zhang,Yuan Fang,Dongdong Tang,Xingyu Xu,Xiaoqian Zhu,Shusheng Wu,Hui Yu,Huiru Cheng,Ting Luo,Qunshan Shen,Yang Gao,Cong Ma,Yajing Liu,Zhaolian Wei,Xiaoyu Chen,Fangbiao Tao,Xiaojin He,Yunxia Cao

PeerJ 10:e13461 PubMed35607451

2022

Melatonin increases growth properties in human dermal papilla spheroids by activating AKT/GSK3β/β-Catenin signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Sowon Bae,Yoo Gyeong Yoon,Ji Yea Kim,In-Chul Park,Sungkwan An,Jae Ho Lee,Seunghee Bae

Investigative ophthalmology & visual science 63:6 PubMed35506935

2022

Melatonin Attenuates LPS-Induced Proinflammatory Cytokine Response and Lipogenesis in Human Meibomian Gland Epithelial Cells via MAPK/NF-κB Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Ren Liu,Jing Li,Yue Xu,Ziyan Chen,Huijing Ye,Jinhui Tang,Lai Wei,Lingyi Liang

Oxidative medicine and cellular longevity 2022:7420726 PubMed35087617

2022

Melatonin Improves the Resistance of Oxidative Stress-Induced Cellular Senescence in Osteoporotic Bone Marrow Mesenchymal Stem Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Weikai Chen,Nanning Lv,Hao Liu,Chao Gu,Xinfeng Zhou,Wanjin Qin,Angela Carley Chen,Liang Chen,Huilin Yang,Xi Chen,Tao Liu,Fan He

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Melatonin Receptor 1A/MTNR1A antibody

Flow Cytometry - Anti-Melatonin Receptor 1A/MTNR1A antibody (AB203038)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (21)

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