AB87639

Anti-Melatonin Receptor 1A/MTNR1A antibody

Name: Anti-Melatonin Receptor 1A/MTNR1A antibody (ab87639) | Abcam
Brand: Abcam Limited
SKU: AB87639
Price: 525 USD
Availability: InStock
Rating: 4 (2 reviews)

(2 Reviews)

(14 Publications)

Goat Polyclonal Melatonin Receptor 1A/MTNR1A antibody. Suitable for WB and reacts with Rat samples. Cited in 14 publications. Immunogen corresponding to Synthetic Peptide within Human Melatonin receptor type 1A aa 100-150.

View Alternative Names

Melatonin receptor type 1A, Mel-1A-R, Mel1a receptor, MTNR1A

1 Images

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Western blot - Anti-Melatonin Receptor 1A/MTNR1A antibody (AB87639)

All lanes:

Western blot - Anti-Melatonin Receptor 1A/MTNR1A antibody (ab87639) at 0.1 µg/mL

All lanes:

Rat Retina lysate at 35 µg

Predicted band size: 39 kDa

Observed band size: 45 kDa

true

Exposure time: 1hr

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Rat

Applications

applications

Immunogen

Synthetic Peptide within Human Melatonin receptor type 1A aa 100-150. The exact immunogen used to generate this antibody is proprietary information.

P48039

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.1-0.3 µg/mL", "WB-species-notes": "<p>1 hour primary incubation is recommended for this product.</p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Storage buffer

pH: 7.3 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 0.5% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

See full target information Melatonin receptor type 1A

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Publications (14)

Recent publications for all applications. Explore the full list and refine your search

BMC genomics 26:242 PubMed40082769

2025

Transcriptomic and proteomic analyses of sclera in lens-induced myopic guinea pigs.

Applications

Unspecified application

Species

Unspecified reactive species

He-Yan Li,Xu-Han Shi,Li Dong,Chu-Yao Yu,Yi-Tong Li,Rui-Heng Zhang,Wen-Da Zhou,Hao-Tian Wu,Jost B Jonas,Wen-Bin Wei

International journal of immunopathology and pharmacology 39:3946320251318147 PubMed39936565

2025

Melatonin alleviates oral epithelial cell inflammation via Keap1/Nrf2 signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Nan Zhang,Wenjing Wang,Rongxia Zhang,Yaxuan Liu,Yamei Wang,Yang Bai,Chencong Li

International journal of molecular sciences 24: PubMed37569373

2023

The Photoperiod-Driven Cyclical Secretion of Pineal Melatonin Regulates Seasonal Reproduction in Geese ().

Applications

Unspecified application

Species

Unspecified reactive species

Qiang Bao,Wang Gu,Lina Song,Kaiqi Weng,Zhengfeng Cao,Yu Zhang,Yang Zhang,Ting Ji,Qi Xu,Guohong Chen

Animals : an open access journal from MDPI 13: PubMed37370427

2023

Photoperiod Induces DNA Methylation Changes in the Melatonin Receptor 1A Gene in Ewes.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoyun He,Wei Wang,Wei Sun,Mingxing Chu

Journal of pineal research 72:e12787 PubMed35133672

2022

Activation of melatonin receptor 1 by CRISPR-Cas9 activator ameliorates cognitive deficits in an Alzheimer's disease mouse model.

Applications

Unspecified application

Species

Unspecified reactive species

Hanseul Park,Jongpil Kim

Animals : an open access journal from MDPI 11: PubMed34201764

2021

Testicular Melatonin and Its Pathway in Roe Deer Bucks () during Pre- and Post-Rut Periods: Correlation with Testicular Involution.

Applications

Unspecified application

Species

Unspecified reactive species

Alberto Elmi,Nadia Govoni,Augusta Zannoni,Martina Bertocchi,Chiara Bernardini,Monica Forni,Domenico Ventrella,Maria Laura Bacci

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 256:110634 PubMed34119649

2021

The probiotic Lactobacillus rhamnosus mimics the dark-driven regulation of appetite markers and melatonin receptors' expression in zebrafish (Danio rerio) larvae: Understanding the role of the gut microbiome.

Applications

Unspecified application

Species

Unspecified reactive species

Esmail Lutfi,Danilo Basili,Silvia Falcinelli,Luis Morillas,Oliana Carnevali,Encarnación Capilla,Isabel Navarro

Frontiers in physiology 11:408 PubMed32435203

2020

Photoperiod Affects Harderian Gland Morphology and Secretion in Female : Autophagy, Apoptosis, and Mitochondria.

Applications

Unspecified application

Species

Unspecified reactive species

Zhe Wang,Jin-Hui Xu,Jun-Jie Mou,Xiao-Tong Kong,Ming Wu,Hui-Liang Xue,Lai-Xiang Xu

RSC advances 10:11264-11273 PubMed35495343

2020

A study of the mechanism of small-molecule soybean-protein-derived peptide supplement to promote sleep in a mouse model.

Applications

Unspecified application

Species

Unspecified reactive species

Guofu Yi,Bushra Safdar,Yihao Zhang,You Li,Xinqi Liu

International journal of molecular sciences 21: PubMed31947744

2020

Age Associated Decrease of MT-1 Melatonin Receptor in Human Dermal Skin Fibroblasts Impairs Protection Against UV-Induced DNA Damage.

Applications

Unspecified application

Species

Unspecified reactive species

Kelly Dong,Earl Goyarts,Antonella Rella,Edward Pelle,Yung Hou Wong,Nadine Pernodet

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Melatonin Receptor 1A/MTNR1A antibody

Western blot - Anti-Melatonin Receptor 1A/MTNR1A antibody (AB87639)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Product protocols

Target data

Publications (14)

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