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AB236546

Anti-Mesothelin antibody [MSLN/2131]

3

(1 Review)

|

(2 Publications)

Mouse Monoclonal Mesothelin antibody. Suitable for IHC-P, Protein Array and reacts with Mouse, Rat, Human, Recombinant full length protein - Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human MSLN aa 250-450.

View Alternative Names

MPF, MSLN, Mesothelin, CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor

6 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelin antibody [MSLN/2131] (AB236546)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelin antibody [MSLN/2131] (AB236546)

Formalin-fixed, paraffin-embedded human endometrial carcinoma tissue stained for Mesothelin using ab236546 at 2 μg/ml in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelin antibody [MSLN/2131] (AB236546)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelin antibody [MSLN/2131] (AB236546)

Formalin-fixed, paraffin-embedded human tonsil tissue stained for Mesothelin using ab236546 at 2 μg/ml in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelin antibody [MSLN/2131] (AB236546)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelin antibody [MSLN/2131] (AB236546)

Formalin-fixed, paraffin-embedded human lung mesothelioma tissue stained for Mesothelin using ab236546 at 2 μg/ml in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelin antibody [MSLN/2131] (AB236546)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelin antibody [MSLN/2131] (AB236546)

Formalin-fixed, paraffin-embedded rat stomach tissue stained for Mesothelin using ab236546 at 2 μg/ml in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelin antibody [MSLN/2131] (AB236546)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mesothelin antibody [MSLN/2131] (AB236546)

Formalin-fixed, paraffin-embedded mouse lung tissue stained for Mesothelin using ab236546 at 2 μg/ml in immunohistochemical analysis.

Protein Array - Anti-Mesothelin antibody [MSLN/2131] (AB236546)
  • Protein Array

Unknown

Protein Array - Anti-Mesothelin antibody [MSLN/2131] (AB236546)

ab236546 was tested in protein array against over 19000 different full-length human proteins.
Z- and S- Score : The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.
A MAb is specific to its intended target if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

  • Biotin

    Biotin Anti-Mesothelin antibody [MSLN/2131]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

MSLN/2131

Isotype

IgG2b

Light chain type

kappa

Carrier free

No

Reacts with

Mouse, Rat, Human

Applications

IHC-P, Protein Array

applications

Immunogen

Recombinant Fragment Protein within Human MSLN aa 250-450. The exact immunogen used to generate this antibody is proprietary information.

Q13421

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ProteinArray" : {"fullname" : "Protein Array", "shortname":"Protein Array"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1-2 µg/mL", "IHCP-species-notes": "<p>Primary incubation for 30 minutes at room temperature.</p>", "ProteinArray-species-checked": "guaranteed", "ProteinArray-species-dilution-info": "", "ProteinArray-species-notes": "" }, "Mouse": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1-2 µg/mL", "IHCP-species-notes": "<p>Primary incubation for 30 minutes at room temperature.</p>", "ProteinArray-species-checked": "guaranteed", "ProteinArray-species-dilution-info": "", "ProteinArray-species-notes": "" }, "Rat": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1-2 µg/mL", "IHCP-species-notes": "<p>Primary incubation for 30 minutes at room temperature.</p>", "ProteinArray-species-checked": "guaranteed", "ProteinArray-species-dilution-info": "", "ProteinArray-species-notes": "" }, "Recombinant full length protein - Human": { "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ProteinArray-species-checked": "testedAndGuaranteed", "ProteinArray-species-dilution-info": "", "ProteinArray-species-notes": "<p></p>" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Purification notes
Purified from Bioreactor Concentrate by Protein A/G.
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Membrane-anchored forms may play a role in cellular adhesion.. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
See full target information MSLN

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Vaccines 13: PubMed40266223

2025

Anti-Tumor Efficacy of a Mesothelin-Based Nanovaccine in a KPC Orthotopic Mouse Model of Pancreatic Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Daniele P Ferrari,Özmen Çobanoglu,Sana Sayedipour,Omar Luna,Sonia A M Ferkel,David Agorku,Yomkippur Perez,Luis J Cruz,Fernando Albericio,François Trottein,Frauke Alves,Marietta Andrea Markus,Fernanda Ramos-Gomes

Pediatric research 97:1209-1219 PubMed39103629

2024

Slow rewarming after hypothermia does not ameliorate white matter injury after hypoxia-ischemia in near-term fetal sheep.

Applications

Unspecified application

Species

Unspecified reactive species

Alice McDouall,Kelly Q Zhou,Anthony Davies,Guido Wassink,Timothy L M Jones,Laura Bennet,Alistair J Gunn,Joanne O Davidson
View all publications

Product promise

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