Rabbit Polyclonal Metabotropic Glutamate Receptor 3/MGLUR3 antibody. N-terminal. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human GRM3.
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Publications
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- Cell death & disease 12:7232021Inhibition of metabotropic glutamate receptor III facilitates sensitization to alkylating chemotherapeutics in glioblastoma.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJulian P Maier,Vidhya M Ravi,Jan Kueckelhaus,Simon P Behringer,Niklas Garrelfs,Paulina Will,Na Sun,Jasmin von Ehr,Jonathan M Goeldner,Dietmar Pfeifer,Marie Follo,Luciana Hannibal,Axel Karl Walch,Ulrich G Hofmann,Jürgen Beck,Dieter Henrik Heiland,Oliver Schnell,Kevin JosephPubMed 34290229
- FASEB journal : official publication of the Federa 33:13734-137462019Localization of group II and III metabotropic glutamate receptors at pre- and postsynaptic sites of inner hair cell ribbon synapses.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLisa Klotz et. al.PubMed 31585509
- Journal of psychopharmacology (Oxford, England) 31:1519-15262017A group II metabotropic glutamate receptor 3 (mGlu3, GRM3) isoform implicated in schizophrenia interacts with canonical mGlu3 and reduces ligand binding.Applications:WBReactive species:Unspecified reactive speciesAintzane García-Bea et. al.PubMed 28655286
- Journal of neuroendocrinology 29:2017Molecular Profiling of Human Induced Pluripotent Stem Cell-Derived Hypothalamic Neurones Provides Developmental Insights into Genetic Loci for Body Weight Regulation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesL Yao,Y Liu,Z Qiu,S Kumar,J E Curran,J Blangero,Y Chen,D M LehmanPubMed 28071834
- Schizophrenia research 177:18-272016Metabotropic glutamate receptor 3 (mGlu3; mGluR3; GRM3) in schizophrenia: Antibody characterisation and a semi-quantitative western blot study.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human GRM3. The exact immunogen used to generate this antibody is proprietary information. Database link Q14832
Consider this alternative
Reactivity data
Select an application| IHC-P | ICC/IF | |
|---|---|---|
| Human | Tested | Tested |
| Mouse | Predicted | Predicted |
| Rat | Predicted | Predicted |
| Common marmoset | Predicted | Predicted |
| Cow | Predicted | Predicted |
| Gorilla | Predicted | Predicted |
| Horse | Predicted | Predicted |
| Monkey | Predicted | Predicted |
| Orangutan | Predicted | Predicted |
| Pig | Predicted | Predicted |
| Rabbit | Predicted | Predicted |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 5-10 µg/mL | Notes Perform heat-mediated antigen retrieval before commencing with IHC staining protocol. |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat, Rabbit, Horse, Cow, Pig, Monkey, Gorilla, Common marmoset, Orangutan | Dilution info - | Notes - |
ICC/IF
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 5-15 µg/mL | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat, Rabbit, Horse, Cow, Pig, Monkey, Gorilla, Common marmoset, Orangutan | Dilution info - | Notes - |
Associated Products
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Target data
Function
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
Alternative names
GPRC1C, MGLUR3, GRM3, Metabotropic glutamate receptor 3, mGluR3
Recommended products
Rabbit Polyclonal Metabotropic Glutamate Receptor 3/MGLUR3 antibody. N-terminal. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human GRM3.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human GRM3. The exact immunogen used to generate this antibody is proprietary information. Database link Q14832
- Purification technique
- Affinity purification Immunogen
- Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
7 product images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Metabotropic Glutamate Receptor 3/MGLUR3 antibody - N-terminal (ab188750)
Immunohistochemical analysis of Human Kidney tissue labeling Metabotropic Glutamate Receptor 3/MGLUR3 using ab188750 at 10 μg/ml.
Immunocytochemistry/ Immunofluorescence - Anti-Metabotropic Glutamate Receptor 3/MGLUR3 antibody - N-terminal (ab188750)
Immunocytochemical analysis of HEK293 tissue labeling Metabotropic Glutamate Receptor 3/MGLUR3 using ab188750 at 10 μg/ml.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Metabotropic Glutamate Receptor 3/MGLUR3 antibody - N-terminal (ab188750)
Immunohistochemical analysis of Human Testies tissue labeling Metabotropic Glutamate Receptor 3/MGLUR3 using ab188750 at 10 μg/ml.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Metabotropic Glutamate Receptor 3/MGLUR3 antibody - N-terminal (ab188750)
Immunohistochemical analysis of Human skin melanoma tissue labeling Metabotropic Glutamate Receptor 3/MGLUR3 using ab188750 at 10 μg/ml.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Metabotropic Glutamate Receptor 3/MGLUR3 antibody - N-terminal (ab188750)
Immunohistochemical analysis of Human brain, Glioblastoma tissue labeling Metabotropic Glutamate Receptor 3/MGLUR3 using ab188750 at 10 μg/ml.
Immunocytochemistry/ Immunofluorescence - Anti-Metabotropic Glutamate Receptor 3/MGLUR3 antibody - N-terminal (ab188750)
Immunocytochemistry of HEK293 Human embryonic kidney cells transfected with Metabotropic Glutamate Receptor 3/MGLUR3 using ab188750 at 10ug/ml.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Metabotropic Glutamate Receptor 3/MGLUR3 antibody - N-terminal (ab188750)
Immunohistochemical analysis of Human brain, coroid plexus tissue labeling Metabotropic Glutamate Receptor 3/MGLUR3 using ab188750 at 38 μg/ml.
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