Rabbit Polyclonal Metabotropic Glutamate Receptor 7/MGLUR7 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human GRM7.
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Publications
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- Nature communications 14:82882023Homo- and hetero-dimeric subunit interactions set affinity and efficacy in metabotropic glutamate receptors.Applications:Unspecified applicationReactive species:Unspecified reactive speciesChris Habrian,Naomi Latorraca,Zhu Fu,Ehud Y IsacoffPubMed 38092773
- Nature communications 10:55722019Conformational pathway provides unique sensitivity to a synaptic mGluR.Applications:Unspecified applicationReactive species:Unspecified reactive speciesChris H Habrian et. al.PubMed 31804469
- Neuroreport 22:244-82011Spinal metabotropic glutamate receptor 4 is involved in neuropathic pain.Applications:Unspecified applicationReactive species:Unspecified reactive speciesHua Wang,Wei Jiang,Rui Yang,Yong LiPubMed 21358553
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human GRM7. The exact immunogen used to generate this antibody is proprietary information. Database link Q14831
Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Human | Tested | Tested |
| Mouse | Predicted | Predicted |
| Rat | Predicted | Predicted |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500.00000 - 1/1000.00000 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat | Dilution info - | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat | Dilution info - | Notes - |
Associated Products
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2 products for Alternative Product
Target data
Function
G-protein coupled receptor activated by glutamate that regulates axon outgrowth through the MAPK-cAMP-PKA signaling pathway during neuronal development (PubMed:33500274). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase that it inhibits (PubMed:9473604).
Alternative names
GPRC1G, MGLUR7, GRM7, Metabotropic glutamate receptor 7, mGluR7
Recommended products
Rabbit Polyclonal Metabotropic Glutamate Receptor 7/MGLUR7 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human GRM7.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human GRM7. The exact immunogen used to generate this antibody is proprietary information. Database link Q14831
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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2 product images
Western blot - Anti-Metabotropic Glutamate Receptor 7/MGLUR7 antibody (ab53705)
All lanes: Western blot - Anti-Metabotropic Glutamate Receptor 7/MGLUR7 antibody (ab53705) at 1/500 dilution
Lane 1: HuvEc cell extract
Lane 2: HuvEc cell extract with immunising peptide
Predicted band size: 102 kDa
Observed band size: 102 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Metabotropic Glutamate Receptor 7/MGLUR7 antibody (ab53705)
ab53705 at 1/50 dilution staining Metabotropic Glutamate Receptor 7/MGLUR7 in human brain by Immunohistochemsitry, Paraffin embedded tissue, in the absence or presence of the immunising peptide.
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