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AB180496

Anti-MFSD7 antibody [EPR13776]

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(1 Publication)

Rabbit Recombinant Monoclonal MFSD7 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.

View Alternative Names

MFSD7, LP2561, UNQ385/PRO717, SLC49A3, Solute carrier family 49 member A3, Major facilitator superfamily domain-containing protein 7, Myosin light polypeptide 5 regulatory protein, MYL5

1 Images
Western blot - Anti-MFSD7 antibody [EPR13776] (AB180496)
  • WB

Supplier Data

Western blot - Anti-MFSD7 antibody [EPR13776] (AB180496)

All lanes:

Western blot - Anti-MFSD7 antibody [EPR13776] (ab180496) at 1/50000 dilution

Lane 1:

Human fetal kidney lysate at 20 µg

Lane 2:

293T lysate at 20 µg

Lane 3:

MCF7 lysate at 20 µg

Lane 4:

HeLa lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 58 kDa

false

  • Carrier free

    Anti-MFSD7 antibody [EPR13776] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR13776

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/10000 - 1/50000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purity
Tissue culture supernatant
Storage buffer
Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

MFSD7 also known as Major Facilitator Superfamily Domain-Containing Protein 7 plays a role in cellular transport mechanisms. This protein facilitates the translocation of various substrates across cell membranes acting as a transporter within the major facilitator superfamily. It has a molecular mass of approximately 55 kDa. Expression of MFSD7 is found in the central nervous system specifically within regions of the brain suggesting its importance in neural processes.
Biological function summary

MFSD7 is involved in maintaining cellular homeostasis by regulating the uptake and release of molecules within neurons and other cell types. It functions as part of a transport complex that modulates intracellular and extracellular concentrations of metabolites important for cellular functions. The protein supports energy metabolism and mediates the intracellular redistribution of bioactive molecules essential for the maintenance of cellular health and function.

Pathways

MFSD7 participates in critical cellular pathways related to energy metabolism and neurological function. It is involved in the facilitation of the tricarboxylic acid (TCA) cycle by promoting the uptake of necessary substrates thereby influencing cellular respiration. MFSD7 collaborates with proteins such as GLUT1 to ensure the efficient transport of nutrients required for energy production and neural activity coordinating cellular bioenergetics and neural signaling pathways.

MFSD7 has notable associations with neurological conditions including Alzheimer's disease and epilepsy. Alterations in MFSD7 expression or function can disrupt neuronal metabolism contributing to these disorders' pathophysiology. In Alzheimer's MFSD7 interacts with the amyloid precursor protein (APP) influencing plaque formation and metabolic disruptions. Its involvement in epilepsy involves regulatory pathways impacting neurotransmitter balance with potential connections to ionic transport mechanisms.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information SLC49A3
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Open biology 7: PubMed28878041

2017

Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression.

Applications

Unspecified application

Species

Unspecified reactive species

Emelie Perland,Sonchita Bagchi,Axel Klaesson,Robert Fredriksson
View all publications
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Product promise

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For full details, please see our Terms & Conditions

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