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AB250199

Anti-MFSD7 antibody [EPR13776] - BSA and Azide free

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Rabbit Recombinant Monoclonal MFSD7 antibody. Carrier free. Suitable for WB and reacts with Human samples.

View Alternative Names

MFSD7, LP2561, UNQ385/PRO717, SLC49A3, Solute carrier family 49 member A3, Major facilitator superfamily domain-containing protein 7, Myosin light polypeptide 5 regulatory protein, MYL5

1 Images
Western blot - Anti-MFSD7 antibody [EPR13776] - BSA and Azide free (AB250199)
  • WB

Supplier Data

Western blot - Anti-MFSD7 antibody [EPR13776] - BSA and Azide free (AB250199)

This data was developed using ab180496, the same antibody clone in a different buffer formulation.

All lanes:

Western blot - Anti-MFSD7 antibody [EPR13776] (<a href='/en-us/products/primary-antibodies/mfsd7-antibody-epr13776-ab180496'>ab180496</a>) at 1/50000 dilution

Lane 1:

Human fetal kidney lysate at 20 µg

Lane 2:

293T lysate at 20 µg

Lane 3:

MCF7 lysate at 20 µg

Lane 4:

HeLa lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 58 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR13776

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

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Product details

ab250199 is the carrier-free version of ab180496.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Compatibility
This product is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar® is a trademark of Fluidigm Canada Inc.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Storage buffer
pH: 7.2 - 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

MFSD7 also known as Major Facilitator Superfamily Domain-Containing Protein 7 plays a role in cellular transport mechanisms. This protein facilitates the translocation of various substrates across cell membranes acting as a transporter within the major facilitator superfamily. It has a molecular mass of approximately 55 kDa. Expression of MFSD7 is found in the central nervous system specifically within regions of the brain suggesting its importance in neural processes.
Biological function summary

MFSD7 is involved in maintaining cellular homeostasis by regulating the uptake and release of molecules within neurons and other cell types. It functions as part of a transport complex that modulates intracellular and extracellular concentrations of metabolites important for cellular functions. The protein supports energy metabolism and mediates the intracellular redistribution of bioactive molecules essential for the maintenance of cellular health and function.

Pathways

MFSD7 participates in critical cellular pathways related to energy metabolism and neurological function. It is involved in the facilitation of the tricarboxylic acid (TCA) cycle by promoting the uptake of necessary substrates thereby influencing cellular respiration. MFSD7 collaborates with proteins such as GLUT1 to ensure the efficient transport of nutrients required for energy production and neural activity coordinating cellular bioenergetics and neural signaling pathways.

MFSD7 has notable associations with neurological conditions including Alzheimer's disease and epilepsy. Alterations in MFSD7 expression or function can disrupt neuronal metabolism contributing to these disorders' pathophysiology. In Alzheimer's MFSD7 interacts with the amyloid precursor protein (APP) influencing plaque formation and metabolic disruptions. Its involvement in epilepsy involves regulatory pathways impacting neurotransmitter balance with potential connections to ionic transport mechanisms.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information SLC49A3
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com