JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB183041

Anti-mH2A1 antibody [EPR9359(2)]

5

(2 Reviews)

|

(14 Publications)

Rabbit Recombinant Monoclonal mH2A1 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human, Mouse samples. Cited in 14 publications.

View Alternative Names

H2AFY, MACROH2A1, Core histone macro-H2A.1, Histone macroH2A1, mH2A1, Histone H2A.y, Medulloblastoma antigen MU-MB-50.205, H2A/y

10 Images
Immunocytochemistry/ Immunofluorescence - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)

Immunofluorescent analysis of 4% paraformaldehyde-fixed MCF7 cells labeling mH2A1 with ab183041 at 1/250 dilution followed by Goat anti rabbit IgG (Alexa Fluor® 488) at 1/200 dilution (green). Counter stained with Dapi (blue).

Immunocytochemistry/ Immunofluorescence - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)
  • ICC/IF

Lab

Immunocytochemistry/ Immunofluorescence - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)

ab183041 staining mH2A1 in HAP1 WT and H2AFY knockout cells. The cells were fixed with 100% methanol (5min), permeabilized with 0.1%PBS-Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1%PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab183041 at 1μg/ml and ab195889, Mouse monoclonal [DM1A] to alpha Tubulin - Microtubule Marker (Alexa Fluor® 594) at 1/250 dilution (shown in pseudocolor red). Cells were then incubated with ab150081, Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (Alexa Fluor® 488) at 1/1000 dilution (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).

Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)

Immunohistochemical analysis of paraffin-embedded Human kidney tissue labeling mH2A1 with ab183041 at 1/100 dilution followed by prediluted HRP Polymer for Rabbit IgG. Counter stained with Hematoxylin.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)

Immunohistochemical analysis of paraffin-embedded Human liver tissue labeling mH2A1 with ab183041 at 1/100 dilution followed by prediluted HRP Polymer for Rabbit IgG. Counter stained with Hematoxylin.

Immunocytochemistry/ Immunofluorescence - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)

Immunofluorescent analysis of acetone-fixed HeLa cells labeling mH2A1 with ab183041 at 1/250 dilution followed by Goat anti rabbit IgG (Alexa Fluor® 488) at 1/200 dilution (green). Counter stained with Dapi (blue).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)
  • IHC-P

AbReview57326****

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse liver from wild-type and mH2A1/2 knock out tissue sections labeling mH2A1 with ab183041 at 1/400 dilution. Sections were fixed in formaldehyde; heat mediated antigen retivial was performed using a citrate buffer pH 6. An undiluted polyclonal horse anti-rabbit IgG (HRP-conjugated) was used as the secondary antibody.

This image is courtesy of an anonymous abreview.

Western blot - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)
  • WB

Lab

Western blot - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)

Lanes 1- 2 : Merged signal (red and green). Green - ab183041 observed at 40 kDa. Red - Anti-alpha Tubulin antibody [DM1A] - Loading Control (ab7291) observed at 50 kDa.

ab183041 was shown to react with mH2A1 in wild-type HEK-293T cells in western blot. The band observed in CRISPR/Cas9 edited cell line ab266241 (CRISPR/Cas9 edited cell lysate ab257463) lane below 40kDa may represent truncated forms and cleaved fragments. This has not been investigated further. Wild-type HEK-293T and H2AFY CRISPR/Cas9 edited HEK-293T cell lysates were subjected to SDS-PAGE. Membrane was blocked for 1 hour at room temperature in 0.1% TBST with 3% non-fat dried milk. ab183041 and Anti-alpha Tubulin antibody [DM1A] - Loading Control (ab7291) were incubated overnight at 4°C at a 1 in 1000 Dilution and a 1 in 20000 dilution respectively. Blots were developed with Goat anti-Rabbit IgG H&L (IRDye®800CW) preadsorbed (ab216773) and Goat anti-Mouse IgG H&L (IRDye®680RD) preadsorbed (ab216776) secondary antibodies at 1 in 20000 dilution for 1 hour at room temperature before imaging.

All lanes:

Western blot - Anti-mH2A1 antibody [EPR9359(2)] (ab183041) at 1/1000 dilution

Lane 1:

Wild-type HEK-293T cell lysate at 20 µg

Lane 2:

H2AFY CRISPR/Cas9 edited HEK-293T cell lysate at 20 µg

Lane 2:

Western blot - Human H2AFY (mH2A1) knockout HEK-293T cell line (<a href='/en-us/products/cell-lines/human-h2afy-mh2a1-knockout-hek-293t-cell-line-ab266241'>ab266241</a>)

Predicted band size: 40 kDa

Observed band size: 40 kDa

false

Western blot - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)
  • WB

Lab

Western blot - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)

Lanes 1- 2 : Merged signal (red and green). Green - ab183041 observed at 40 kDa. Red - Anti-alpha Tubulin antibody [DM1A] - Loading Control (ab7291) observed at 50 kDa.

ab183041 was shown to react with mH2A1 in wild-type HEK-293T cells in western blot. The band observed in knockout cell line ab266241 (knockout cell lysate ab257463) lane below 40kDa may represent truncated forms and cleaved fragments. This has not been investigated further. Wild-type HEK-293T and H2AFY knockout HEK-293T cell lysates were subjected to SDS-PAGE. Membrane was blocked for 1 hour at room temperature in 0.1% TBST with 3% non-fat dried milk. ab183041 and Anti-alpha Tubulin antibody [DM1A] - Loading Control (ab7291) were incubated overnight at 4°C at a 1 in 1000 Dilution and a 1 in 20000 dilution respectively. Blots were developed with Goat anti-Rabbit IgG H&L (IRDye®800CW) preadsorbed (ab216773) and Goat anti-Mouse IgG H&L (IRDye®680RD) preadsorbed (ab216776) secondary antibodies at 1 in 20000 dilution for 1 hour at room temperature before imaging.

All lanes:

Western blot - Anti-mH2A1 antibody [EPR9359(2)] (ab183041) at 1/1000 dilution

Lane 1:

Wild-type HEK-293T cell lysate at 20 µg

Lane 2:

H2AFY knockout HEK-293T cell lysate at 20 µg

Predicted band size: 40 kDa

Observed band size: 40 kDa

false

Western blot - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)
  • WB

Lab

Western blot - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)

Lane 1 : Wild type HAP1 whole cell lysate (20 μg)
Lane 2 : mH2A1 knockout HAP1 whole cell lysate (20 μg)
Lane 3 : HeLa whole cell lysate (20 μg)
Lane 4 : Hepg2 whole cell lysate (20 μg)

Lanes 1 - 4 : Merged signal (red and green). Green - ab183041 observed at 40 kDa. Red - loading control, ab18058, observed at 130 kDa.

ab183041 was shown to specifically react with mH2A1 when mH2A1 knockout samples were used. Wild-type and mH2A1 knockout samples were subjected to SDS-PAGE. ab183041 and ab18058 (Mouse anti Vinculin loading control) were incubated overnight at 4°C at 10000 dilution and 1/10000 dilution respectively. Blots were developed with Goat anti-Rabbit IgG H&L (IRDye® 800CW) preabsorbed ab216773 and Goat anti-Mouse IgG H&L (IRDye® 680RD) preabsorbed ab216776 secondary antibodies at 1/10000 dilution for 1 hour at room temperature before imaging.

All lanes:

Western blot - Anti-mH2A1 antibody [EPR9359(2)] (ab183041)

Predicted band size: 40 kDa

false

Western blot - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)
  • WB

Supplier Data

Western blot - Anti-mH2A1 antibody [EPR9359(2)] (AB183041)

All lanes:

Western blot - Anti-mH2A1 antibody [EPR9359(2)] (ab183041) at 1/50000 dilution

Lane 1:

HepG2 cell lysate at 20 µg

Lane 2:

MCF7 cell lysate at 20 µg

Lane 3:

HeLa cell lysate at 20 µg

Lane 4:

293T cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Predicted band size: 40 kDa

Observed band size: 40 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR9359(2)

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

ICC/IF, IHC-P, WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style
left-column

Alternative Products

Primary Antibodies

AB37264

Anti-mH2A1 antibody

BOND RX™ Validated|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-mH2A1 antibody (AB37264)

  • 4
  • 5
Primary Antibodies

AB137117

Anti-mH2A1 antibody [EPR9358]

RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-mH2A1 antibody [EPR9358] (AB137117)

  • 4
  • 1
Primary Antibodies

AB91528

Anti-mH2A1 antibody [14G7]

KO Validated

Flow Cytometry (Intracellular) - Anti-mH2A1 antibody [14G7] (AB91528)

  • 4
  • 1

Complementary Products

Primary Antibodies

AB1791

Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade

Lab Essentials

ChIP - Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade (AB1791)

  • 5
  • 233
Primary Antibodies

AB16048

Anti-Lamin B1 antibody - Nuclear Envelope Marker

BOND RX™ Validated|KO Validated|Lab Essentials

Western blot - Anti-Lamin B1 antibody - Nuclear Envelope Marker (AB16048)

  • 5
  • 110
Primary Antibodies

AB10158

Anti-Histone H4 antibody - ChIP Grade

BOND RX™ Validated

Western blot - Anti-Histone H4 antibody - ChIP Grade (AB10158)

  • 4
  • 21
Primary Antibodies

AB1790

Anti-Histone H2B antibody - ChIP Grade

BOND RX™ Validated

Western blot - Anti-Histone H2B antibody - ChIP Grade (AB1790)

  • 5
  • 28
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/100", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/10000 - 1/50000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1 µg/mL", "ICCIF-species-notes": "<p>This antibody gives positive signal in both 4%PFA and 100% MeOH-fixed cells.</p>" }, "Mouse": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/100", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/10000 - 1/50000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "1 µg/mL", "ICCIF-species-notes": "<p>This antibody gives positive signal in both 4%PFA and 100% MeOH-fixed cells.</p>" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
style
left-column

Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

MH2A1 also known as macroH2A1 is a histone variant with a distinguished structure characterized by an extended C-terminal macro domain. It has a molecular mass of approximately 42-45 kDa. This histone variant is widely expressed across various tissues showing particularly high levels in differentiated cells. mH2A1 incorporates into chromatin impacting nucleosome stability and chromatin dynamics. Researchers have also identified an isoform known as H2AFY which further highlights the structural complexity and versatile roles of mH2A1 in cellular regulation.
Biological function summary

MH2A1 plays significant roles in chromatin remodeling and gene expression regulation. It is part of the nucleosome replacing canonical histone H2A and influencing the accessibility of chromatin to transcriptional machinery. Through this function mH2A1 can repress or activate gene expression depending on cellular context and interacting partners. Its incorporation into chromatin is associated with the silencing of certain genomic regions such as inactive X chromosome in females with potential implications for epigenetic modifications and cellular differentiation.

Pathways

MH2A1 is notably involved in pathways regulating chromatin organization and cell differentiation. It plays a role in the Polycomb Repressive Complex 2 (PRC2) pathway affecting histone methylation and gene silencing. Furthermore mH2A1 interacts with proteins like EZH2 in PRC2 which carry out methylation at histone H3 on lysine 27. These interactions highlight mH2A1's involvement in maintaining repressive chromatin states and controlling gene expression patterns important for normal cell function.

MH2A1 is connected with cancer and metabolic diseases. Its altered expression has been observed in various cancers where it might impact tumor progression by modulating genes linked to proliferation and differentiation. mH2A1 influences pathways shared with proteins like BRAC1 that are involved in DNA repair processes. Additionally changes in mH2A1 expression are linked to metabolic disorders especially those affecting lipid metabolism and insulin responses suggesting its potential role in regulating metabolic pathways and influencing disease progression.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription (PubMed : 12718888, PubMed : 15621527, PubMed : 16428466). Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template (PubMed : 15897469). Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability (PubMed : 15897469). DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Involved in stable X chromosome inactivation (PubMed : 15897469). Inhibits the binding of transcription factors, including NF-kappa-B, and interferes with the activity of remodeling SWI/SNF complexes (PubMed : 12718888, PubMed : 16428466). Inhibits histone acetylation by EP300 and recruits class I HDACs, which induces a hypoacetylated state of chromatin (PubMed : 16107708, PubMed : 16428466).. Isoform 1. Isoform that specifically binds poly-ADP-ribose and O-acetyl-ADP-ribose and plays a key role in NAD(+) metabolism (PubMed : 15902274). Able to bind to the ends of poly-ADP-ribose chains created by PARP1 and cap them (By similarity). This prevents PARP1 from further addition of ADP-ribose and thus limits the consumption of nuclear NAD(+), allowing the cell to maintain proper NAD(+) levels in both the nucleus and the mitochondria to promote proper mitochondrial respiration (By similarity). Increases the expression of genes involved in redox metabolism, including SOD3 (PubMed : 23022728).. Isoform 2. In contrast to isoform 1, does not bind poly-ADP-ribose (PubMed : 15902274). Represses SOD3 gene expression (PubMed : 23022728).
See full target information MACROH2A1
style
left-column

Publications (14)

Recent publications for all applications. Explore the full list and refine your search

Cell & bioscience 13:170 PubMed37705092

2023

A distinct circular DNA profile intersects with proteome changes in the genotoxic stress-related hSOD1 model of ALS.

Applications

Unspecified application

Species

Unspecified reactive species

Daniela Gerovska,Julie B Noer,Yating Qin,Quratul Ain,Donjetë Januzi,Matthias Schwab,Otto W Witte,Marcos J Araúzo-Bravo,Alexandra Kretz

PLoS pathogens 18:e1010353 PubMed35395063

2022

Parvovirus nonstructural protein 2 interacts with chromatin-regulating cellular proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Salla Mattola,Kari Salokas,Vesa Aho,Elina Mäntylä,Sami Salminen,Satu Hakanen,Einari A Niskanen,Julija Svirskaite,Teemu O Ihalainen,Kari J Airenne,Minna Kaikkonen-Määttä,Colin R Parrish,Markku Varjosalo,Maija Vihinen-Ranta

Frontiers in immunology 12:723293 PubMed34899687

2021

Exploring the Prognostic Value, Immune Implication and Biological Function of Gene in Hepatocellular Carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yongbiao Huang,Shanshan Huang,Li Ma,Yali Wang,Xi Wang,Lingyan Xiao,Wan Qin,Long Li,Xianglin Yuan

Genome biology 22:309 PubMed34749781

2021

TAD-like single-cell domain structures exist on both active and inactive X chromosomes and persist under epigenetic perturbations.

Applications

Unspecified application

Species

Unspecified reactive species

Yubao Cheng,Miao Liu,Mengwei Hu,Siyuan Wang

Nucleic acids research 49:8024-8036 PubMed34223906

2021

LSH catalyzes ATP-driven exchange of histone variants macroH2A1 and macroH2A2.

Applications

Unspecified application

Species

Unspecified reactive species

Kai Ni,Kathrin Muegge

Nature communications 12:3520 PubMed34112784

2021

The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoping Xu,Kai Ni,Yafeng He,Jianke Ren,Chongkui Sun,Yie Liu,Mirit I Aladjem,Sandra Burkett,Richard Finney,Xia Ding,Shyam K Sharan,Kathrin Muegge

Molecular cell 81:1566-1577.e8 PubMed33657402

2021

Genome oligopaint via local denaturation fluorescence in situ hybridization.

Applications

Unspecified application

Species

Unspecified reactive species

Yanbo Wang,Wayne Taylor Cottle,Haobo Wang,Xinyu Ashlee Feng,John Mallon,Momcilo Gavrilov,Scott Bailey,Taekjip Ha

Life sciences 263:118576 PubMed33058912

2020

Upregulated mH2A1 serves as an unfavorable prognostic indicator and promotes the progress of hepatocellular carcinoma (HCC).

Applications

Unspecified application

Species

Unspecified reactive species

Guangchao Yang,Yuanfei Yao,Dehai Wu,Hongrui Guo,Shuo Zhou,Dan Sun,Xinyu Guo,Tongsen Zheng,Jiabei Wang,Shugeng Zhang,Yan Wang,Ruipeng Song,Shanjia Ke,Yao Liu,Fanzheng Meng,Yingjian Liang,Zhaoyang Lu,Lianxin Liu

Nature methods 17:822-832 PubMed32719531

2020

3D mapping and accelerated super-resolution imaging of the human genome using in situ sequencing.

Applications

Unspecified application

Species

Unspecified reactive species

Huy Q Nguyen,Shyamtanu Chattoraj,David Castillo,Son C Nguyen,Guy Nir,Antonios Lioutas,Elliot A Hershberg,Nuno M C Martins,Paul L Reginato,Mohammed Hannan,Brian J Beliveau,George M Church,Evan R Daugharthy,Marc A Marti-Renom,C-Ting Wu

Scientific reports 9:3161 PubMed30816182

2019

Tissue Engineered Neural Constructs Composed of Neural Precursor Cells, Recombinant Spidroin and PRP for Neural Tissue Regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

V P Baklaushev,V G Bogush,V A Kalsin,N N Sovetnikov,E M Samoilova,V A Revkova,K V Sidoruk,M A Konoplyannikov,P S Timashev,S L Kotova,K B Yushkov,A V Averyanov,A V Troitskiy,J-E Ahlfors
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com