Skip to main content

Rabbit Polyclonal Morphine antibody. Suitable for ELISA and reacts with Chemical samples. Immunogen corresponding to Chemical / Small Molecule corresponding to Morphine.

Be the first to review this product! Submit a review

Key facts

Isotype
IgG
Host species
Rabbit
Storage buffer

Constituents: Whole serum

Form
Liquid
Clonality
Polyclonal

Immunogen

  • Chemical / Small Molecule corresponding to Morphine.

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
ELISA
Chemical
Expected

Expected
Expected

Species
Chemical
Dilution info
Use at an assay dependent concentration.
Notes

-

Alternative names

Recommended products

Rabbit Polyclonal Morphine antibody. Suitable for ELISA and reacts with Chemical samples. Immunogen corresponding to Chemical / Small Molecule corresponding to Morphine.

Key facts

Isotype
IgG
Form
Liquid
Clonality
Polyclonal
Immunogen
  • Chemical / Small Molecule corresponding to Morphine.
Purity
Whole antiserum
Concentration
Loading...
Purification notes

Purity is greater than or equal to 98% by SDS PAGE. No contaminants detected. Single band by SDS PAGE, IEP, and/or RID.

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Add glycerol to a final volume of 50% for extra stability and aliquot
Storage information
Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.
Activity summary

Morphine is an alkaloid compound with a molecular mass of about 285.34 g/mol. It is obtained from the opium poppy plant and serves as a potent analgesic. Morphine acts by binding to and activating mu-opioid receptors (MOR) which are widely expressed in the central nervous system including the brain and spinal cord. This interaction reduces the perception of pain. In addition it affects delta and kappa opioid receptors to a lesser extent modulating various sensory and emotional responses.

Biological function summary

Morphine serves as an important player in pain management and sedation processes. It does not function as part of any complex but directly interacts with its target receptors. Morphine not only alters pain perception but also impacts emotions and mood due to its interactions in the brain. This changes how the nervous system responds to pain stimuli providing relief in conditions where pain management is necessary. Antimorphine compounds can antagonize these effects reversing morphine's actions on the nervous system.

Pathways

Morphine participates in the opioid receptor signaling pathway and is fundamentally involved in the modulation of neurotransmission. This pathway also draws connections with other proteins like G-proteins and secondary messengers leading to inhibition of adenylyl cyclase and decreased cAMP production. These processes result in reduced neurotransmitter release fortifying morphine's role as an analgesic. Morphine's action in these pathways mirrors that of similar agents like endorphins and enkephalins which share receptor affinity but are endogenously produced.

Associated diseases and disorders

Morphine usage relates significantly to pain management in conditions like chronic pain and post-surgical pain. However repeated use can lead to substance use disorders or opioid addiction highlighting a critical concern in therapeutic settings. The potential for addiction involves complex interactions with proteins like dopamine receptors which contribute to the reinforcement mechanisms. Effective pain management strategies often consider the role of antimorphine formulations to counteract these effects and prevent dependency.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

0 product images

    Downloads

    Product protocols

    For this product, it's our understanding that no specific protocols are required. You can:

    Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

    For licensing inquiries, please contact partnerships@abcam.com