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AB30683

Anti-Morphine antibody

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(1 Publication)

Rabbit Polyclonal Morphine antibody. Suitable for ELISA and reacts with Chemical samples. Cited in 1 publication. Immunogen corresponding to Chemical / Small Molecule corresponding to Morphine.

View Alternative Names

Morphine 6

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Applications

ELISA

applications

Reactivity data

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Properties and storage information

Form
Liquid
Purity
Whole antiserum
Purification notes
Purity is greater than or equal to 98% by SDS PAGE. No contaminants detected. Single band by SDS PAGE, IEP, and/or RID.
Storage buffer
Constituents: Whole serum
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Add glycerol to a final volume of 50% for extra stability and aliquot
Storage information
Avoid freeze / thaw cycle

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Morphine is an alkaloid compound with a molecular mass of about 285.34 g/mol. It is obtained from the opium poppy plant and serves as a potent analgesic. Morphine acts by binding to and activating mu-opioid receptors (MOR) which are widely expressed in the central nervous system including the brain and spinal cord. This interaction reduces the perception of pain. In addition it affects delta and kappa opioid receptors to a lesser extent modulating various sensory and emotional responses.
Biological function summary

Morphine serves as an important player in pain management and sedation processes. It does not function as part of any complex but directly interacts with its target receptors. Morphine not only alters pain perception but also impacts emotions and mood due to its interactions in the brain. This changes how the nervous system responds to pain stimuli providing relief in conditions where pain management is necessary. Antimorphine compounds can antagonize these effects reversing morphine's actions on the nervous system.

Pathways

Morphine participates in the opioid receptor signaling pathway and is fundamentally involved in the modulation of neurotransmission. This pathway also draws connections with other proteins like G-proteins and secondary messengers leading to inhibition of adenylyl cyclase and decreased cAMP production. These processes result in reduced neurotransmitter release fortifying morphine's role as an analgesic. Morphine's action in these pathways mirrors that of similar agents like endorphins and enkephalins which share receptor affinity but are endogenously produced.

Morphine usage relates significantly to pain management in conditions like chronic pain and post-surgical pain. However repeated use can lead to substance use disorders or opioid addiction highlighting a critical concern in therapeutic settings. The potential for addiction involves complex interactions with proteins like dopamine receptors which contribute to the reinforcement mechanisms. Effective pain management strategies often consider the role of antimorphine formulations to counteract these effects and prevent dependency.

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 39:e71051 PubMed40955587

2025

NONO Maintains SREBP-Regulated Cholesterol Biosynthesis via RNA Binding in Neuroblastoma.

Applications

Unspecified application

Species

Unspecified reactive species

Song Zhang,Hayley Ingram,Jack Cooper,Alina Naveed,Stefan G Kathman,Garrett L Lindsey,Tao Liu,Charles S Bond,Jamie I Fletcher,Benjamin F Cravatt,Archa H Fox
View all publications

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