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AB272635

Anti-MOSPD3 antibody

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Rabbit Polyclonal MOSPD3 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human MOSPD3 aa 50-200.

View Alternative Names

Motile sperm domain-containing protein 3, MOSPD3

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MOSPD3 antibody (AB272635)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MOSPD3 antibody (AB272635)

Paraffin-embedded formalin-fixed Human urinary tissue stained for MOSPD3 using ab272635 at 1/2500 in immunohistochemical analysis.

Immunocytochemistry/ Immunofluorescence - Anti-MOSPD3 antibody (AB272635)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-MOSPD3 antibody (AB272635)

PFA fixed, Triton X-100 permeablized human cell line A431 labeling MOSPD3 (green) using ab272635 at 2 ug/ml in ICC/IF analysis.

Western blot - Anti-MOSPD3 antibody (AB272635)
  • WB

Unknown

Western blot - Anti-MOSPD3 antibody (AB272635)

All lanes:

Western blot - Anti-MOSPD3 antibody (ab272635) at 0.4 µg/mL

Lane 1:

Control (vector only transfected HEK-293T lysate)

Lane 2:

MOSPD3 over-expression lysate (mammalian HEK-293T cells)

Predicted band size: 26 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human MOSPD3 aa 50-200. The exact immunogen used to generate this antibody is proprietary information.

O75425

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/1000 - 1/2500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

MOSPD3 or Motile Sperm Domain Containing 3 is a protein with an approximate mass of 49 kDa. It is known to be expressed broadly across various human tissues including the brain heart and skeletal muscle. MOSPD3 contains a motile sperm domain indicating its potential involvement in cellular motility processes. Researchers have identified it as a part of the family of proteins that contain the MSP domain which plays a role in membrane-related functions.
Biological function summary

MOSPD3 participates in cellular development and organization processes. The protein seems to interact with specific membrane structures suggesting its role in intracellular signaling and transport. It might be involved in the organization of microtubule structures supporting cellular architecture. Although there is limited data on its participation in a distinct complex the protein interacts with various cytoskeletal and signaling components.

Pathways

Studies link MOSPD3 to cellular pathways that regulate cytoskeletal dynamics and cell motility. It plays a role in pathways such as the Wnt signaling pathway which influences cell proliferation and differentiation. In these processes MOSPD3 interacts with proteins like dishevelled segment polarity protein (DVL) contributing to signal transduction and effective cellular communication.

MOSPD3 has been associated with neurological disorders due to its expression in brain tissues. Altered function or expression may contribute to conditions like autism spectrum disorder. Furthermore its expression in cardiovascular tissues connects MOSPD3 to cardiomyopathy a disease affecting heart muscle function. In these diseases MOSPD3 might interact with proteins like titin which are critical for maintaining structural integrity within tissues.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information MOSPD3
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Product promise

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For full details, please see our Terms & Conditions

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