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AB193435

Anti-MPT64 antibody

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(1 Publication)

Rabbit Polyclonal MPT64 antibody. Suitable for WB, ELISA and reacts with Transfected cell lysate - Mycobacterium tuberculosis, Mycobacterium tuberculosis samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Mycobacterium tuberculosis CDC1551 mpt64.

View Alternative Names

MT2032, mpt64, Immunogenic protein MPT64, Antigen MPT64

1 Images
Western blot - Anti-MPT64 antibody (AB193435)
  • WB

Supplier Data

Western blot - Anti-MPT64 antibody (AB193435)

Lane 1 : Positive WB detected in : MPT64 293T Transfected lysate.

Lane 2 : 293T non-Transfected lysate.

ab193435 antibody at 1 : 2000 dilution. Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.

Predicted band size : 51 kDa Observed band size : 51 kDa.

All lanes:

Western blot - Anti-MPT64 antibody (ab193435)

Predicted band size: 25 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mycobacterium tuberculosis

Applications

WB, ELISA

applications

Immunogen

Recombinant Full Length Protein corresponding to Mycobacterium tuberculosis CDC1551 mpt64.

P9WIN8

Specificity

Reacts with Mycobacterium tuberculosis.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mycobacterium tuberculosis": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>" }, "Transfected cell lysate - Mycobacterium tuberculosis": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "ELISA-species-checked": "notRecommended", "ELISA-species-dilution-info": "", "ELISA-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
>95%,Protein G purified
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The MPT64 protein also known as the Mycobacterium tuberculosis 64-kDa protein or Rv1980c is an immunogenic protein with a mass of around 24.7 kDa. It is secreted by Mycobacterium tuberculosis a bacterium responsible for the infectious disease tuberculosis (TB). MPT64 is expressed during the active replication stages of this pathogen playing a role in its life cycle. MPT64 is recognized by the host immune system which makes it an important marker in diagnostic tests for TB.
Biological function summary

MPT64 interacts with the host's immune cell processes impacting the ability of Mycobacterium tuberculosis to survive and persist in the host. MPT64 is part of a larger complex of secreted proteins that modulate the host's immune response aiding in the pathogen's evasion of immune detection. Through these mechanisms MPT64 contributes to the pathogen's virulence. The protein's activity is important in maintaining the infectious cycle by interfering with host defenses and sustaining bacterial growth and spread.

Pathways

MPT64's role in disrupting host immune pathways is significant for tuberculosis progression. It interacts primarily with host signaling pathways linked to the immune response. Although not many pathways are thoroughly mapped for MPT64 its interaction with proteins involved in the regulation of antigen processing and presentation is evident. Such interactions can affect how the immune system recognizes and eliminates Mycobacterium tuberculosis highlighting MPT64's role in immune evasion.

MPT64 is directly associated with tuberculosis a major global health issue. It is valuable both as a diagnostic target and as a predictor of active TB infection. Tuberculosis caused by Mycobacterium tuberculosis involves MPT64 as an important factor in its pathogenesis. MPT64's connection with ESAT-6 another Mycobacterium tuberculosis antigen highlights its involvement in immune system modulation and disease progression highlighting its significance in infectious disease research.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information mpt64

Additional targets

MPT64
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Molecular medicine reports 24: PubMed34558650

2021

Exosomes in serum‑free cultures of THP‑1 macrophages infected with .

Applications

Unspecified application

Species

Unspecified reactive species

Fantahun Biadglegne,Phil Rademacher,Yarúa Gabriela Jaimes De Sulbaran,Brigitte König,Arne C Rodloff,Ulrike Zedler,Anca Dorhoi,Ulrich Sack
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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Associated Products

Select an associated product type
Alternative Product
Primary Antibodies

AB193387

HRP Anti-MPT64 antibody

primary-antibodies

hrp-mpt64-antibody-ab193387

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