Rabbit Polyclonal MRP-L9 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human MRPL9 aa 1-200.
IgG
Rabbit
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)
Liquid
Polyclonal
IHC-P | WB | ICC/IF | |
---|---|---|---|
Human | Tested | Tested | Tested |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 1/50.00000 - 1/200.00000 | Notes Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 0.04000-0.40000 µg/mL | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 0.25000-2.00000 µg/mL | Notes - |
Select an associated product type
Large ribosomal subunit protein bL9m, L9mt, MRP-L9, MRPL9
Rabbit Polyclonal MRP-L9 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human MRPL9 aa 1-200.
IgG
Rabbit
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)
Liquid
Polyclonal
Affinity purification Immunogen
Blue Ice
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
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This supplementary information is collated from multiple sources and compiled automatically.
The MRP-L9 protein also known as 39S ribosomal protein L9 mitochondrial functions as a structural component of the mitochondrial ribosome. It plays an important role in protein synthesis within the mitochondria part of the 39S large subunit of the ribosome. MRP-L9 has a molecular mass of approximately 18 kDa. This protein is typically expressed in mitochondria across various tissues maintaining essential processes required for cellular energy production.
MRP-L9 contributes to mitochondrial translation apparatus. It integrates into the mitochondrial ribosome complex facilitating the translation of mitochondrial-encoded proteins. These proteins include components necessary for oxidative phosphorylation. The proper functioning of this translation machinery requires the interaction and coordination of MRP-L9 with other ribosomal proteins and assembly factors ensuring mitochondrial integrity and the production of energy.
The involvement of MRP-L9 in mitochondrial translation is connected to broader cellular energy metabolism. MRP-L9 is part of the oxidative phosphorylation pathway which generates ATP by electron transport and chemiosmosis. It is related to other proteins such as MRP-L12 which also plays a role in mitochondrial protein synthesis and energy production. Disruptions in these pathways can affect cellular energy balance and lead to metabolic disturbances.
Mutations or dysfunctions involving MRP-L9 may relate to mitochondrial disorders. Such conditions can manifest in energy-related syndromes such as mitochondrial myopathy affecting muscle function due to impaired oxidative phosphorylation. MRP-L9 is linked with the COX3 protein where any disruption can influence mitochondrial respiratory chain complexes further contributing to the pathology of these disorders. Understanding the role of MRP-L9 in these diseases helps in exploring potential therapeutic strategies.
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This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
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Terms & Conditions.
ab121287, at a 1/50 dilution, staining MRP-L9 in glandular cells of paraffin-embedded Human small intestine tissue by immunohistochemistry.
ab121287, at 4 μg/ml, staining MRP-L9 (shown in green) in Human cell line U-2 OS cells by immunofluorescence.
All lanes: Western blot - Anti-MRP-L9 antibody (ab121287) at 1/250 dilution
Lane 1: RT-4 cell lysate
Lane 2: U-251 MG cell lysate
Lane 3: Human plasma
Lane 4: Human liver lysate
Lane 5: Human tonsil lysate
Predicted band size: 30 kDa
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