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Rabbit Polyclonal MRP-L9 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human MRPL9 aa 1-200.

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Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRP-L9 antibody (AB121287), expandable thumbnail
  • Immunocytochemistry/ Immunofluorescence - Anti-MRP-L9 antibody (AB121287), expandable thumbnail
  • Western blot - Anti-MRP-L9 antibody (AB121287), expandable thumbnail

Publications

Key facts

Isotype

IgG

Host species

Rabbit

Storage buffer

pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)

Form

Liquid

Clonality

Polyclonal

Immunogen

  • Recombinant Fragment Protein within Human MRPL9 aa 1-200. The exact immunogen used to generate this antibody is proprietary information. Database link Q9BYD2

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
IHC-PWBICC/IF
Human
Tested
Tested
Tested

Tested
Tested

Species

Human

Dilution info

1/50.00000 - 1/200.00000

Notes

Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Tested
Tested

Species

Human

Dilution info

0.04000-0.40000 µg/mL

Notes

-

Tested
Tested

Species

Human

Dilution info

0.25000-2.00000 µg/mL

Notes

-

Associated Products

Select an associated product type

1 product for Alternative Product

Alternative names

Recommended products

Rabbit Polyclonal MRP-L9 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human MRPL9 aa 1-200.

Key facts

Isotype

IgG

Form

Liquid

Clonality

Polyclonal

Immunogen
  • Recombinant Fragment Protein within Human MRPL9 aa 1-200. The exact immunogen used to generate this antibody is proprietary information. Database link Q9BYD2
Purification technique

Affinity purification Immunogen

Concentration
Loading...

Storage

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

The MRP-L9 protein also known as 39S ribosomal protein L9 mitochondrial functions as a structural component of the mitochondrial ribosome. It plays an important role in protein synthesis within the mitochondria part of the 39S large subunit of the ribosome. MRP-L9 has a molecular mass of approximately 18 kDa. This protein is typically expressed in mitochondria across various tissues maintaining essential processes required for cellular energy production.

Biological function summary

MRP-L9 contributes to mitochondrial translation apparatus. It integrates into the mitochondrial ribosome complex facilitating the translation of mitochondrial-encoded proteins. These proteins include components necessary for oxidative phosphorylation. The proper functioning of this translation machinery requires the interaction and coordination of MRP-L9 with other ribosomal proteins and assembly factors ensuring mitochondrial integrity and the production of energy.

Pathways

The involvement of MRP-L9 in mitochondrial translation is connected to broader cellular energy metabolism. MRP-L9 is part of the oxidative phosphorylation pathway which generates ATP by electron transport and chemiosmosis. It is related to other proteins such as MRP-L12 which also plays a role in mitochondrial protein synthesis and energy production. Disruptions in these pathways can affect cellular energy balance and lead to metabolic disturbances.

Associated diseases and disorders

Mutations or dysfunctions involving MRP-L9 may relate to mitochondrial disorders. Such conditions can manifest in energy-related syndromes such as mitochondrial myopathy affecting muscle function due to impaired oxidative phosphorylation. MRP-L9 is linked with the COX3 protein where any disruption can influence mitochondrial respiratory chain complexes further contributing to the pathology of these disorders. Understanding the role of MRP-L9 in these diseases helps in exploring potential therapeutic strategies.

Product promise

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In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
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3 product images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRP-L9 antibody (ab121287), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRP-L9 antibody (ab121287)

    ab121287, at a 1/50 dilution, staining MRP-L9 in glandular cells of paraffin-embedded Human small intestine tissue by immunohistochemistry.

  • Immunocytochemistry/ Immunofluorescence - Anti-MRP-L9 antibody (ab121287), expandable thumbnail

    Immunocytochemistry/ Immunofluorescence - Anti-MRP-L9 antibody (ab121287)

    ab121287, at 4 μg/ml, staining MRP-L9 (shown in green) in Human cell line U-2 OS cells by immunofluorescence.

  • Western blot - Anti-MRP-L9 antibody (ab121287), expandable thumbnail

    Western blot - Anti-MRP-L9 antibody (ab121287)

    All lanes: Western blot - Anti-MRP-L9 antibody (ab121287) at 1/250 dilution

    Lane 1: RT-4 cell lysate

    Lane 2: U-251 MG cell lysate

    Lane 3: Human plasma

    Lane 4: Human liver lysate

    Lane 5: Human tonsil lysate

    Predicted band size: 30 kDa

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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