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AB181058

Anti-MRPL20 antibody [EPR12592]

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(1 Publication)

Rabbit Recombinant Monoclonal MRPL20 antibody. Suitable for WB and reacts with Human, Mouse, Rat samples. Cited in 1 publication.

View Alternative Names

Large ribosomal subunit protein bL20m, L20mt, MRP-L20, MRPL20

1 Images
Western blot - Anti-MRPL20 antibody [EPR12592] (AB181058)
  • WB

Supplier Data

Western blot - Anti-MRPL20 antibody [EPR12592] (AB181058)

All lanes:

Western blot - Anti-MRPL20 antibody [EPR12592] (ab181058) at 1/1000 dilution

Lane 1:

HUVEC cell lysate at 10 µg

Lane 2:

HeLa cell lysate at 10 µg

Lane 3:

C6 cell lysate at 10 µg

Lane 4:

RAW 264.7 cell lysate at 10 µg

Lane 5:

PC12 cell lysate at 10 µg

Lane 6:

NIH 3T3 cell lysate at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L) HRP at 1/1000 dilution

Predicted band size: 17 kDa

false

  • Carrier free

    Anti-MRPL20 antibody [EPR12592] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR12592

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Rat, Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/2000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/2000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/2000", "WB-species-notes": "<p></p>" } } }
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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purity
Tissue culture supernatant
Storage buffer
Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

MRPL20 or mitochondrial ribosomal protein L20 is a component of the mitochondrial ribosome involved in protein synthesis within the mitochondria. MRPL20 weighs around 27 kDa and is key in the formation and function of the mitochondrial large ribosomal subunit. It is expressed ubiquitously with high levels in tissues that demand significant energy such as the brain heart and skeletal muscle.
Biological function summary

MRPL20 plays a role in protein assembly within mitochondria forming part of the 39S ribosomal subunit. It interacts with RNA and other ribosomal proteins to ensure proper mitochondrial protein translation. MRPL20 works in close relationship with other mitochondrial ribosomal proteins such as MRPL3 and MRPL15 facilitating efficient mitochondrial biogenesis and energy production.

Pathways

The MRPL20 protein is significant in the mitochondrial translation pathway which is important for respiratory chain complex assembly. It aids in encoding proteins necessary for oxidative phosphorylation. MRPL20 associates with proteins like MRPS12 and MRPS18A which participate in mitochondrial protein synthesis integrating into the broader mitochondrial function and energy production network.

MRPL20 is linked to mitochondrial dysfunction and related diseases such as mitochondrial encephalomyopathy and cardiomyopathy. These conditions can result from mutations affecting MRPL20 disrupting mitochondrial protein synthesis and impairing energy production. MRPL20 interacts with proteins like MFN2 which are also involved in mitochondrial maintenance and have roles in disorders related to energy deficits in the human body.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information MRPL20
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Oxidative medicine and cellular longevity 2022:7856290 PubMed35464758

2022

Novel piRNA Regulates PIWIL1 to Modulate the Behavior of Placental Trophoblast Cells and Participates in Preeclampsia.

Applications

Unspecified application

Species

Unspecified reactive species

Jing Lin,Ye Zhou,Wei Gu
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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