Anti-MRPL34 antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

MRPL34 is part of the large subunit of the mitochondrial ribosome which assembles with the small subunit to translate mitochondrial-encoded proteins essential for the oxidative phosphorylation system. Within the mitochondrial ribosome which is composed of roughly 50 distinct proteins and 2 ribosomal RNA molecules MRPL34 contributes to the formation and stabilization of the ribosomal RNA core structure. Its involvement in mitochondrial protein translation directly affects cellular energy metabolism and overall mitochondrial function.

Pathways

MRPL34 contributes to the mitochondrial translation pathway an essential part of maintaining the electron transport chain by facilitating the synthesis of core components required for oxidative phosphorylation. Key proteins involved in these processes include cytochrome c oxidase and ATP synthase essential for energy production. MRPL34 ensures the proper assembly of these complexes by aiding the accurate translation of mitochondrial genome-encoded proteins.