Anti-MRPL42 antibody [OTI1A4]

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

MRPL42 contributes to mitochondrial protein synthesis by being part of the ribosomal structure responsible for translating mitochondrial mRNA into functional proteins. It integrates into the mitochondrial ribosome complex specifically binding to the 39S subunit. This integration enables the synthesis of proteins that are encoded by mitochondrial DNA including those critical for oxidative phosphorylation a process essential for cellular energy production.

Pathways

The function of MRPL42 fits into the broader context of mitochondrial biogenesis and oxidative phosphorylation. It plays a role in the mitochondrial translation pathway facilitating the production of respiratory chain components essential for energy conversion. Proteins like COX1 and ATP synthase subunits are products of these translation processes that MRPL42 influences. By assisting in the translation of these components MRPL42 indirectly supports the electron transport chain and ATP synthesis driving cellular activities.