Rabbit Polyclonal MRPL51 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human MRPL51 aa 50 to C-terminus.
View Alternative Names
MRP64, CDA09, HSPC241, MRPL51, Large ribosomal subunit protein mL51, bMRP-64, L51mt, MRP-L51, bMRP64
- ICC/IF
Supplier Data
Immunocytochemistry/ Immunofluorescence - Anti-MRPL51 antibody (AB243821)
PFA fixed, Triton X-100 permeabilized A431 (Human epidermoid carcinoma cell line) cells labeling MRPL51 using ab243821 at 4 μg/ml (green) in ICC/IF.
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPL51 antibody (AB243821)
Formalin-fixed, paraffin-embedded human duodenum tissue stained for MRPL51 with ab243821 at a 1/50 dilution in immunohistochemical analysis.
- WB
Supplier Data
Western blot - Anti-MRPL51 antibody (AB243821)
All lanes:
Western blot - Anti-MRPL51 antibody (ab243821) at 0.4 µg/mL
Lane 1:
RT4 (Human urinary bladder cancer cell line) cell lysate
Lane 2:
U-251 MG (Human brain glioma cell line) cell lysate
Predicted band size: 15 kDa
false
Alternative Products
Complementary Products
Reactivity data
Properties and storage information
Form
Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
MRPL51 functions as part of the large subunit of the mitochondrial ribosome which is essential for the translation of proteins encoded by mitochondrial DNA. The protein is a component of a much larger ribosomal complex that assembles mRNA translation machinery specific to mitochondria. This complex plays a critical role in maintaining the functionality of mitochondria by ensuring the continuous production of proteins necessary for the electron transport chain and other mitochondrial processes.
Pathways
The ribosomal activity of MRPL51 connects directly to the oxidative phosphorylation pathway one of the most important for energy production within cells. The protein is associated with the synthesis of components essential for ATP generation. MRPL51 also relates to the mitochondrial translation pathway where it interacts with other ribosomal proteins to facilitate protein synthesis. Proteins like POLG the mitochondrial DNA polymerase and other subunits of the ribosome are also involved in these pathways illustrating an integrated role in cellular bioenergetics.
Product protocols
- Visit the General protocols
- Visit the Troubleshooting
Target data
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com