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AB185233

Anti-MRPS26 antibody [EPR14396-90]

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Rabbit Recombinant Monoclonal MRPS26 antibody. Suitable for WB and reacts with Human samples.

View Alternative Names

C20orf193, RPMS13, MRPS26, Small ribosomal subunit protein mS26, MRP-S13, S13mt, MRP-S26, S26mt

1 Images
Western blot - Anti-MRPS26 antibody [EPR14396-90] (AB185233)
  • WB

Supplier Data

Western blot - Anti-MRPS26 antibody [EPR14396-90] (AB185233)

Blocking/diluting buffer 5% NFDM/TBST

All lanes:

Western blot - Anti-MRPS26 antibody [EPR14396-90] (ab185233) at 1/10000 dilution

Lane 1:

HepG2 cell lysate at 20 µg

Lane 2:

Raji cell lysate at 20 µg

Lane 3:

HeLa cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 24 kDa

false

  • Carrier free

    Anti-MRPS26 antibody [EPR14396-90] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR14396-90

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>" } } }

Product details

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

MRPS26 also known as Mitochondrial Ribosomal Protein S26 is a component of the mitochondrial ribosome small subunit (28S) in humans. It has a mass of about 23 kDa and primarily facilitates protein synthesis within mitochondria. MRPS26 is expressed across various tissues but shows a higher expression rate in tissues with high energy demands including the heart skeletal muscle and brain.
Biological function summary

MRPS26 functions as an integral part of the mitochondrial ribosome which is a complex essential for the translation of mitochondrial-encoded proteins. These proteins are critical for maintaining the mitochondrial respiratory chain. MRPS26 contributes to the proper assembly and stability of the ribosomal structure working alongside other mitochondrial ribosomal proteins to ensure efficient protein synthesis within the mitochondria.

Pathways

MRPS26 plays an essential role in the mitochondrial translation pathway related to oxidative phosphorylation. This pathway is important for ATP production driving energy metabolism in aerobic conditions. MRPS26 is also associated with key proteins like MRPS16 and MRPS23 within the mitochondrial ribosomal complex which together facilitate mitochondrial biogenesis and energy conversion processes.

MRPS26 is implicated in conditions linked to mitochondrial dysfunction such as mitochondrial myopathy and neurodegenerative diseases. Mutations or dysregulation within this protein or its associated complex can lead to impaired mitochondrial protein synthesis contributing to these disorders. Proteins such as MRPS22 have also displayed connections to similar pathologies highlighting the cooperative role these ribosomal subunits play in maintaining mitochondrial integrity.

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

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