JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB250827

Anti-MRPS26 antibody [EPR14396-90] - BSA and Azide free

Be the first to review this product! Submit a review

|

(0 Publication)

Rabbit Recombinant Monoclonal MRPS26 antibody. Carrier free. Suitable for WB and reacts with Human samples.

View Alternative Names

C20orf193, RPMS13, MRPS26, Small ribosomal subunit protein mS26, MRP-S13, S13mt, MRP-S26, S26mt

1 Images
Western blot - Anti-MRPS26 antibody [EPR14396-90] - BSA and Azide free (AB250827)
  • WB

Supplier Data

Western blot - Anti-MRPS26 antibody [EPR14396-90] - BSA and Azide free (AB250827)

This data was developed using ab185233, the same antibody clone in a different buffer formulation.

Blocking and dilution buffer : 5% NFDM/TBST.

All lanes:

Western blot - Anti-MRPS26 antibody [EPR14396-90] (<a href='/en-us/products/primary-antibodies/mrps26-antibody-epr14396-90-ab185233'>ab185233</a>) at 1/10000 dilution

Lane 1:

HepG2 cell lysate at 20 µg

Lane 2:

Raji cell lysate at 20 µg

Lane 3:

HeLa cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 24 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR14396-90

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
style
left-column

Product details

ab250827 is the carrier-free version of ab185233.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Compatibility
This product is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar® is a trademark of Fluidigm Canada Inc.

style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 - 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

MRPS26 also known as Mitochondrial Ribosomal Protein S26 is a component of the mitochondrial ribosome small subunit (28S) in humans. It has a mass of about 23 kDa and primarily facilitates protein synthesis within mitochondria. MRPS26 is expressed across various tissues but shows a higher expression rate in tissues with high energy demands including the heart skeletal muscle and brain.
Biological function summary

MRPS26 functions as an integral part of the mitochondrial ribosome which is a complex essential for the translation of mitochondrial-encoded proteins. These proteins are critical for maintaining the mitochondrial respiratory chain. MRPS26 contributes to the proper assembly and stability of the ribosomal structure working alongside other mitochondrial ribosomal proteins to ensure efficient protein synthesis within the mitochondria.

Pathways

MRPS26 plays an essential role in the mitochondrial translation pathway related to oxidative phosphorylation. This pathway is important for ATP production driving energy metabolism in aerobic conditions. MRPS26 is also associated with key proteins like MRPS16 and MRPS23 within the mitochondrial ribosomal complex which together facilitate mitochondrial biogenesis and energy conversion processes.

MRPS26 is implicated in conditions linked to mitochondrial dysfunction such as mitochondrial myopathy and neurodegenerative diseases. Mutations or dysregulation within this protein or its associated complex can lead to impaired mitochondrial protein synthesis contributing to these disorders. Proteins such as MRPS22 have also displayed connections to similar pathologies highlighting the cooperative role these ribosomal subunits play in maintaining mitochondrial integrity.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

See full target information MRPS26
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB232886

Anti-MRPL1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPL1 antibody (AB232886)

  • 0
  • 0
Primary Antibodies

AB194829

Anti-TIM44 antibody [EPR16821]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-TIM44 antibody [EPR16821] (AB194829)

  • 0
  • 0
Primary Antibodies

AB174831

Anti-MMAB antibody [EPR8695]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-MMAB antibody [EPR8695] (AB174831)

  • 0
  • 0
Primary Antibodies

AB137064

Anti-Ndufs4 antibody [EP7832]

RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-Ndufs4 antibody [EP7832] (AB137064)

  • 5
  • 14

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com